Nasrallah Mona P, Nakhoul Nancy F, Nasreddine Lara, Mouneimne Youssef, Abiad Mohamad G, Ismaeel Hussain, Tamim Hani
Endocr Pract. 2017 Sep;23(9):1091-1100. doi: 10.4158/EP171876.OR. Epub 2017 Jul 6.
The Middle East North Africa region has one of the highest rates of diabetes, both in prevalence and in rate of increase. The aim of this study was to examine the prevalence and associated risk factors of type 2 diabetes mellitus (T2D) in the adult population of Beirut.
A random sample of 501 men and women aged 18 to 79 years was examined in a cross-sectional manner. The sample was then divided into 3 groups based on T2D self-report, glycosylated hemoglobin (HbA1c), and fasting glucose (no diabetes [ND], at risk for diabetes [RD], and probable diabetes [PD]). These were compared to determine the various associated risks.
The sample consisted of 64.3% women, with an average age of 45.4 ± 15 years, and a mean body mass index (BMI) of 29.4 ± 5.9 kg/m. The subjects were predominantly from a low socio-economic status, and more than half smoked either cigarettes or a waterpipe. The percentages of the 3 groups were as follows: 41.7%, 40.3%, and 18.0% for ND, RD, and PD, respectively. Out of 90 subjects diagnosed with PD, 26 did not know they had diabetes. Independent, positively associated risk factors were age, BMI, heart rate, hypertension, triglyceride, and high-density lipoprotein cholesterol.
The prevalence of T2D was high in this study and seems to be increasing compared to prior diabetes reports. Overall, the whole sample had a high prevalence of cardiovascular risk factors such as smoking, obesity, and physical inactivity. However, subjects with diabetes had significantly more components of the metabolic syndrome.
ADA = American Diabetes Association CRP = C-reactive protein DD = definite diabetes FPG = fasting plasma glucose HbA1c = glycosylated hemoglobin MENA = Middle-East North Africa ND = no diabetes PD = probable diabetes RD = at risk of diabetes T2D = type 2 diabetes mellitus TSH = thyroid-stimulating hormone.
中东和北非地区的糖尿病患病率及增长率均位居世界前列。本研究旨在调查贝鲁特成年人群中2型糖尿病(T2D)的患病率及其相关危险因素。
采用横断面研究方法,随机抽取501名年龄在18至79岁之间的男性和女性作为样本。然后根据T2D自我报告、糖化血红蛋白(HbA1c)和空腹血糖水平将样本分为三组(无糖尿病[ND]、糖尿病风险[RD]和疑似糖尿病[PD])。通过比较这三组来确定各种相关风险。
样本中女性占64.3%,平均年龄为45.4±15岁,平均体重指数(BMI)为29.4±5.9kg/m²。研究对象主要来自社会经济地位较低的群体,超过半数的人吸烟或吸食水烟。三组的比例分别为:ND组41.7%,RD组40.3%,PD组18.0%。在90名被诊断为PD的受试者中,有26人不知道自己患有糖尿病。独立的正相关危险因素包括年龄、BMI、心率、高血压、甘油三酯和高密度脂蛋白胆固醇。
本研究中T2D的患病率较高,与之前的糖尿病报告相比似乎呈上升趋势。总体而言,整个样本中吸烟、肥胖和缺乏运动等心血管危险因素的患病率较高。然而,糖尿病患者的代谢综合征成分明显更多。
ADA = 美国糖尿病协会;CRP = C反应蛋白;DD = 确诊糖尿病;FPG = 空腹血糖;HbA1c = 糖化血红蛋白;MENA = 中东和北非;ND = 无糖尿病;PD = 疑似糖尿病;RD = 糖尿病风险;T2D = 2型糖尿病;TSH = 促甲状腺激素