Lu You, Wang Ningjian, Chen Yi, Nie Xiaomin, Li Qin, Han Bing, Chen Yingchao, Xia Fangzhen, Cang Zhen, Lu Meng, Meng Ying, Lu Yingli
Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200011, China.
BMC Endocr Disord. 2017 Jul 6;17(1):38. doi: 10.1186/s12902-017-0187-1.
Used the EuroQoL-5 dimension (EQ-5D) to evaluate the health status of 5310 residents who live in East China, and compared the health-related quality of life (HRQoL) with 311 patients with type 2 diabetes as well as to explore the main influence factors to HRQoL in East China.
The cohort includes 5310 participants aged 18-89 years old lived in East China. EuroQoL-5 dimension (EQ-5D) scale was used for the assessment of health-related quality of life.
The mean age of the cohort was 52.2 ± 13.4 years of which 43.7% were male. A moderate level of health-related quality of life was measured of that EQ-5D index and EQ-VAS scores were 0.939 ± 0.111 and 80.06 ± 11.58, respectively. There was a significant difference between diabetes patients and non-diabetes (p = 0.029, p < 0.001, respectively). The age had an inverse correlation with the EQ-5D scores both in general population and diabetes patients. The EQ-5D Vas was weakly adversely associated with the FPG, HbA1c and HOMA-IR.
The overall health-related quality of life of population in East-China was moderate. Diabetes patients had lower score of health-related quality. The healthy-related quality was associated with the age, gender, economic development of region, level of education and marital status.
采用欧洲五维度健康量表(EQ-5D)评估5310名居住在中国东部地区居民的健康状况,并与311例2型糖尿病患者的健康相关生活质量(HRQoL)进行比较,以探讨影响中国东部地区HRQoL的主要因素。
该队列包括5310名年龄在18 - 89岁之间居住在中国东部地区的参与者。采用欧洲五维度健康量表(EQ-5D)对健康相关生活质量进行评估。
该队列的平均年龄为52.2±13.4岁,其中男性占43.7%。测得的健康相关生活质量处于中等水平,EQ-5D指数和EQ视觉模拟量表(EQ-VAS)得分分别为0.939±0.111和80.06±11.58。糖尿病患者与非糖尿病患者之间存在显著差异(分别为p = 0.029,p < 0.001)。在普通人群和糖尿病患者中,年龄与EQ-5D得分均呈负相关。EQ-VAS与空腹血糖(FPG)、糖化血红蛋白(HbA1c)和稳态模型胰岛素抵抗指数(HOMA-IR)呈弱负相关。
中国东部地区人群总体健康相关生活质量处于中等水平。糖尿病患者的健康相关生活质量得分较低。健康相关生活质量与年龄、性别、地区经济发展、教育水平和婚姻状况有关。