Institute of Burn Research, The First Affiliated Hospital of Army Medical University, Chongqing, 400038, China.
School of Nursing, Chongqing Medical University, Chongqing, 400016, China.
Health Qual Life Outcomes. 2023 Aug 26;21(1):100. doi: 10.1186/s12955-023-02183-1.
Type 2 diabetes mellitus (T2DM) is a chronic and life-threatening disease. Health-related quality of life (HRQoL) is vital for individuals with T2DM. However, little is known about the impact of psychological stability factors on HRQoL among individuals with T2DM in mainland China.
This multicenter cross-sectional study was conducted in five tertiary grade-A hospitals in Chongqing, China, from January to December 2019. A total of 385 individuals with T2DM were included by the convenient sample method. Fear of Progression (FOP) Questionnaire-short Form, Hypoglycemia Fear Survey II, diabetes-management self-efficacy scale, and EuroQol-5 Dimensions were used for data collection.
The mean age of the 385 individuals was 57.65 (SD = 15.15) years, three-quarters of whom had a high school or above education level. The participants in our study had moderate HRQoL and were more likely to have poor scores in the pain/discomfort dimension. The FOP level was moderate on average, and 23.1% of individuals suffered from psychological dysfunction. The participants had higher levels of fear of hypoglycemia (FOH) and self-efficacy (SE). Multiple steppage-regression analysis predicted that higher levels of FOP and FOH, reduced SE, older age, longer duration since diagnosis, lower educational attainment, higher levels of HbA1c, and living with comorbid conditions were related to lower HRQoL.
This study showed that the HRQoL among Chinese T2DM patients may be impaired by increased FOP and FOH, decreased SE, and poor glycemic control. In addition, as the patient's age and duration since diagnosis increase, their HRQoL further declines. We recommend improving HRQoL by encouraging individuals to attain more health education and resilience skills to enhance SE and reduce negative emotions among individuals with T2DM.
2 型糖尿病（T2DM）是一种慢性且危及生命的疾病。健康相关生活质量（HRQoL）对于 T2DM 患者至关重要。然而，在中国内地，关于心理稳定性因素对 T2DM 患者 HRQoL 的影响知之甚少。
本多中心横断面研究于 2019 年 1 月至 12 月在重庆的五家三级甲等医院进行。通过方便样本法纳入了 385 名 T2DM 患者。使用恐惧进展（FOP）问卷短表、低血糖恐惧调查 II、糖尿病管理自我效能量表和欧洲五维健康量表收集数据。
385 名患者的平均年龄为 57.65（SD=15.15）岁，其中四分之三具有高中以上学历。本研究参与者的 HRQoL 处于中等水平，更有可能在疼痛/不适维度上得分较差。FOP 水平平均处于中等水平，23.1%的个体存在心理功能障碍。参与者的低血糖恐惧（FOH）和自我效能（SE）水平较高。多元逐步回归分析预测，较高的 FOP 和 FOH 水平、较低的 SE、较高的年龄、较长的诊断后时间、较低的教育程度、较高的糖化血红蛋白（HbA1c）水平以及合并症的存在与较低的 HRQoL 相关。
本研究表明，中国 T2DM 患者的 HRQoL 可能因 FOP 和 FOH 增加、SE 降低以及血糖控制不佳而受损。此外，随着患者年龄和诊断后时间的增加，其 HRQoL 进一步下降。我们建议通过鼓励患者获得更多的健康教育和适应技能来改善 HRQoL，以增强 SE 并减轻 T2DM 患者的负面情绪。
