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妊娠合并抗N-甲基-D-天冬氨酸受体脑炎患者的椎管内麻醉:剖宫产和卵巢切除术的管理

Neuraxial anesthesia in a patient with anti-N-methyl-D-aspartate receptor encephalitis in pregnancy: management for cesarean delivery and oophorectomy.

作者信息

Demma L, Norris S, Dolak J

机构信息

Department of Anesthesiology, Bassett Healthcare, Cooperstown, NY, USA.

Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA, USA.

出版信息

Int J Obstet Anesth. 2017 May;31:104-107. doi: 10.1016/j.ijoa.2017.05.006. Epub 2017 May 11.

Abstract

We describe the neuraxial anesthetic management of a 28-year-old primigravid patient with severe, treatment-refractory anti-N-methyl-D-aspartate receptor encephalitis undergoing cesarean delivery. The presence of an ovarian teratoma was suspected although not confirmed by imaging. The severity of symptoms, ineffective immunotherapy and the need for chemotherapy necessitated cesarean delivery and resection of a suspected teratoma at 28weeks estimated gestational age. A combined spinal-epidural technique was used. Delivery was uneventful, and a right oophorectomy was performed for a visible lesion that was later confirmed to be a mature cystic teratoma.

摘要

我们描述了一名28岁初产妇的神经轴麻管理情况,该患者患有严重的、治疗难治性抗N-甲基-D-天冬氨酸受体脑炎,正在接受剖宫产。尽管影像学未证实,但怀疑存在卵巢畸胎瘤。症状的严重程度、无效的免疫治疗以及化疗的必要性使得在估计孕周28周时必须进行剖宫产并切除疑似畸胎瘤。采用了腰麻-硬膜外联合技术。分娩过程顺利,对一个可见病变进行了右侧卵巢切除术,后来证实该病变为成熟囊性畸胎瘤。

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