Caicedo Alexander, Thewissen Liesbeth, Smits Anne, Naulaers Gunnar, Allegaert Karel, Van Huffel Sabine
Department of Electrical Engineering, STADIUS-ESAT, KU Leuven, Leuven, Belgium.
imec, Leuven, Belgium.
Adv Exp Med Biol. 2017;977:133-139. doi: 10.1007/978-3-319-55231-6_18.
This study investigates the relationship between brain oxygenation, assessed by means of near infrared spectroscopy (NIRS), and brain function, assessed by means of electroencephalography (EEG). Using NIRS signals measuring the regional cerebral oxygen saturation (rScO) and computing the fractional tissue oxygen extraction (FTOE), we compared how these variables relate to different features extracted from the EEG, such as the inter-burst interval (IBI) duration and amplitude, the amplitude of the EEG, and the amplitude of the burst. A cohort of 22 neonates undergoing sedation by propofol was studied and a regression of the NIRS-derived values to the different EEG features was made. We found that higher values of FTOE were related to higher values of EEG amplitude. These results might be of used in the monitoring of proper brain function in neonates.
本研究调查了通过近红外光谱（NIRS）评估的脑氧合与通过脑电图（EEG）评估的脑功能之间的关系。利用测量局部脑氧饱和度（rScO）的NIRS信号并计算组织氧提取分数（FTOE），我们比较了这些变量与从EEG提取的不同特征之间的关系，如爆发间期（IBI）持续时间和幅度、EEG幅度以及爆发幅度。对22名接受丙泊酚镇静的新生儿进行了研究，并对NIRS衍生值与不同EEG特征进行了回归分析。我们发现FTOE值越高，与EEG幅度值越高相关。这些结果可能有助于监测新生儿的正常脑功能。
