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[抗生素耐药性:欧洲及瑞士的情况以及对医生的影响]

[Antibiotic resistance : situation in Europe and Switzerland, and impact for the physician].

作者信息

Bellini Cristina, Troilet Nicolas

机构信息

Service des maladies infectieuses, Institut Central des Hôpitaux / Hôpital Riviera-Chablais, Boulevard Padewreski 3, 1800 Vevey.

Service des maladies infectieuses, Institut Central des Hôpitaux / Hôpital du Valais, Avenue du Grand-Champsec 86, 1950 Sion.

出版信息

Rev Med Suisse. 2016 Oct 12;12(534):1699-1702.

PMID:28686394
Abstract

Antibiotic-resistant bacteria constitute a major public health challenge worldwide. In Europe and Switzerland, the incidence of infections due to methicillin-resistant S. aureus has been decreasing during the recent years. But common Enterobacteriaceae, such as E. coli and K. pneumoniae are more and more resistant, causing therapeutic difficulties, also in the outpatient setting and for benign infections. To fight this increasing problem, any physician has to apply simple preventive measures against the spread of resistant bacteria during care, and to prevent their selection by an appropriate antibiotic use, including the adjustment of the antibacterial spectrum, right dosage and short duration.

摘要

抗生素耐药菌是全球主要的公共卫生挑战。在欧洲和瑞士,近年来耐甲氧西林金黄色葡萄球菌引起的感染发病率一直在下降。但常见的肠杆菌科细菌,如大肠杆菌和肺炎克雷伯菌的耐药性越来越强,在门诊环境中以及良性感染中也造成了治疗困难。为应对这一日益严重的问题,每位医生都必须采取简单的预防措施,防止耐药菌在护理过程中传播,并通过适当使用抗生素来防止其产生,包括调整抗菌谱、正确的剂量和缩短疗程。

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