Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Asian J Surg. 2018 May;41(3):285-290. doi: 10.1016/j.asjsur.2017.04.003. Epub 2017 Jul 8.
BACKGROUND/OBJECTIVE: Laparoscopic sleeve gastrectomy (LSG) is at present the most popular bariatric procedure due to its significant weight loss, remission of co-morbidities, and acceptable morbidity. But, there are not many studies showing its long term efficacy and safety in Chinese patients. The aim of this study is to give five results of LSG in terms of weight loss, co-morbidity (Type 2 diabetes mellitus) resolution and possible complications from a single center in mainland China.
This is a retrospective study of 218 obese patients who underwent LSG by a single surgeon from June 2011 to June 2016. Patients were subjected to standardized perioperative evaluation and education program. Patients were followed up after 1, 3, 6, 12, 18, and 24 months and yearly thereafter. Long term outcomes in terms of weight loss in kg, % of total weight loss (%TWL), % excess weight loss (%EWL), % resolution of type 2 diabetes mellitus (T2DM) and % complication rate are studied.
The %TWL was 33.8 ± 5.9, 28.8 ± 8.9, 26.6 ± 6.9, 18.0 ± 7.6, 15.0 ± 7.1 and %EWL was 62.8 ± 16.9 (n-96), 49.5 ± 18.5 (n-43), 39.8 ± 13.1 (n-15), 32.2 ± 2.1 (n-13), 19.5 ± 8.7 (n-2) at 1, 2, 3, 4 and 5 years, respectively. T2DM remission rate was 72.9% at one year. There were no major complications like leak, stricture, staple line bleeding, port site herniation and gastro-esophageal reflux disease (GERD). There was no mortality. Most common early complication was port site dehiscence (10%), managed conservatively; none requiring readmission. No reoperation was done for weight regain.
LSG is a safe and effective procedure with good five year results. Weight regain remains a concern two years post surgery. Standardization of LSG is important to reduce major complications.
背景/目的:腹腔镜袖状胃切除术(LSG)是目前最受欢迎的减肥手术,因为它具有显著的减重效果、缓解合并症和可接受的发病率。但是,在中国患者中,很少有研究表明其长期疗效和安全性。本研究旨在从中国大陆的一个中心,提供 LSG 在减重、合并症(2 型糖尿病)缓解和可能并发症方面的五个结果。
这是一项回顾性研究,纳入了 2011 年 6 月至 2016 年 6 月期间由一位外科医生为 218 名肥胖患者进行的 LSG。患者接受了标准化的围手术期评估和教育计划。患者在术后 1、3、6、12、18 和 24 个月以及此后每年进行随访。研究的长期结果包括体重减轻的公斤数、总体重减轻的百分比(%TWL)、多余体重减轻的百分比(%EWL)、2 型糖尿病(T2DM)缓解的百分比和并发症发生率。
TWL 为 33.8±5.9、28.8±8.9、26.6±6.9、18.0±7.6、15.0±7.1,EWL 为 62.8±16.9(n=96)、49.5±18.5(n=43)、39.8±13.1(n=15)、32.2±2.1(n=13)、19.5±8.7(n=2),分别在术后 1、2、3、4 和 5 年。T2DM 缓解率为 72.9%,在术后 1 年。没有出现漏液、狭窄、吻合口出血、切口疝和胃食管反流病(GERD)等主要并发症。无死亡病例。最常见的早期并发症是切口疝(10%),经保守治疗后缓解,无需要再次入院的病例。无因体重反弹而进行再手术的病例。
LSG 是一种安全有效的手术,5 年效果良好。体重反弹仍然是术后 2 年的一个问题。LSG 的标准化对于减少主要并发症很重要。