Wang Xin, Chang Xu-Sheng, Gao Lin, Zheng Cheng-Zhu, Zhao Xin, Yin Kai, Fang Guo-En
Department of General Surgery, Changhai Hospital, The Second Military Medical University, Shanghai 200433, China; Department of Gynaecology and Obstetrics, The 306 Hospital of PLA, Beijing 100037, China.
Department of General Surgery, Yancheng City First People's Hospital, Jiangsu 224000, China.
Surg Obes Relat Dis. 2016 Aug;12(7):1305-1311. doi: 10.1016/j.soard.2016.03.004. Epub 2016 Mar 8.
Laparoscopic sleeve gastrectomy (LSG) is becoming a stand-alone bariatric surgery for obesity, but its effectiveness for Mainland Chinese patients remains unclear.
To evaluate the effectiveness and safety of LSG for Mainland Chinese patients SETTING: A tertiary hospital METHODS: Retrospective analysis of patients admitted for LSG between January 2011 and February 2012 was performed. Medium-term outcome measures were: total weight loss (%TWL), excess weight loss (%EWL), co-morbidities, improvement, and complications.
Seventy patients (body mass index [BMI] 40.8±5.9 kg/m) underwent LSG, comprising 40 women and 30 men. The most common co-morbidity was diabetes (n = 29, 41.4%). Lost to follow-up rate for weight loss was 15.7%, 31.4%, and 41% at 1, 2, and 3 years. The %TWL was 34.4±6.1, 34.7±6.2 and 33.7±7.1 at 1, 2, and 3 years. The %EWL increased to 77.1±13.0, 77.9±12.2 and 77.2±13.1 at 1, 2, and 3years. The proportions of patients having successful weight loss were 100% or 85% at 3 years according the definition of %TWL>10% or %EWL>50%. Approximately 79.3%, 51.7%, and 44.8% of patients completed follow-up for glycemic control at each time point, respectively. The proportions of patients with optimal glycemic control (fasting blood glucose [FBG]<5.6 mmol/L; hemoglobin A1C [HbA1C]<6.5%) were 47.9%, 60.0%, and 69.2% at 1, 2, and 3years. The weight loss and glycemic control effect may be greater in the high BMI group (≥40 kg/m). Early and late complications occurred in 8.6% and 7.1% of patients during follow-up.
LSG is effective in weight loss and glycemic control and is safe for Mainland Chinese obese patients, especially for patients with a BMI≥40 kg/m.
腹腔镜袖状胃切除术（LSG）正成为一种独立的肥胖症减肥手术，但对中国大陆患者的有效性仍不明确。
评估LSG对中国大陆患者的有效性和安全性。
一家三级医院。
对2011年1月至2012年2月期间因LSG入院的患者进行回顾性分析。中期结果指标包括：总体重减轻（%TWL）、多余体重减轻（%EWL）、合并症、改善情况和并发症。
70例患者（体重指数[BMI]40.8±5.9kg/m²）接受了LSG，其中40名女性和30名男性。最常见的合并症是糖尿病（n = 29，41.4%）。体重减轻的失访率在1年、2年和3年分别为15.7%、31.4%和41%。1年、2年和3年时的%TWL分别为34.4±6.1、34.7±6.2和33.7±7.1。1年、2年和3年时的%EWL分别增至77.1±13.0、77.9±12.2和77.2±13.1。根据%TWL>10%或%EWL>50%的定义，3年时体重减轻成功的患者比例为100%或85%。在每个时间点，分别约有79.3%、51.7%和44.8%的患者完成了血糖控制随访。血糖控制达到最佳（空腹血糖[FBG]<5.6mmol/L；糖化血红蛋白[HbA1C]<6.5%）的患者比例在1年、2年和3年分别为47.9%、60.0%和69.2%。高BMI组（≥40kg/m²）的体重减轻和血糖控制效果可能更佳。随访期间，8.6%的患者发生早期并发症，7.1%的患者发生晚期并发症。
LSG对中国大陆肥胖患者，尤其是BMI≥40kg/m²的患者，在体重减轻和血糖控制方面有效且安全。
