一般人群中精神病症状的社会人口学和临床相关性：来自 MHGP 调查的结果。
Sociodemographic and clinical correlates of psychotic symptoms in the general population: Findings from the MHGP survey.
机构信息
CHRU de Lille, Pôle de psychiatrie, Hôpital Fontan, Lille 59000, France; AP-HP, DHU PePSY, Hôpitaux Universitaires Henri-Mondor, Pôle de Psychiatrie, Créteil 94000, France; INSERM, U955, team 15, Créteil 94000, France; Fondation FondaMental, Créteil 94000, France; UPEC, Université Paris-Est, Faculté de Médecine, Créteil 94000, France.
AP-HP, DHU PePSY, Hôpitaux Universitaires Henri-Mondor, Pôle de Psychiatrie, Créteil 94000, France; INSERM, U955, team 15, Créteil 94000, France; Fondation FondaMental, Créteil 94000, France; UPEC, Université Paris-Est, Faculté de Médecine, Créteil 94000, France.
出版信息
Schizophr Res. 2018 Mar;193:336-342. doi: 10.1016/j.schres.2017.06.053. Epub 2017 Jul 8.
BACKGROUND
We aimed to explore the sociodemographic and psychiatric correlates of psychotic symptoms in a large general population sample.
METHODS
The French Mental Health in the General Population cross-sectional survey interviewed 38,694 individuals using the Mini International Neuropsychiatric Interview. We looked for associations between the presence of lifetime psychotic symptoms, sociodemographic characteristics (including migrant status over three generations) and clinical characteristics. We then looked for associations regarding only hallucinations, delusional symptoms, and the co-occurrence of both hallucinations and delusional symptoms. To test the psychosis continuum hypothesis, associations with sociodemographic characteristics were compared with the characterized psychotic disorders' associations.
RESULTS
We found that 22.3% of the population declared psychotic symptoms without psychotic disorders, including 5.7% who declared hallucinations, 20.5% delusional symptoms, 4.0% both hallucinations and delusional symptoms, and 2.8% characterized psychotic disorders. The presence of psychotic symptoms was associated with young age, migrant status (over three generations), secondary education level, low-income level and never-married and separated marital status. Hallucinations, delusional symptoms and the co-occurrence of both hallucinations and delusional symptoms showed the same correlates, and hallucinations were also associated with elementary education level. Characterized psychotic disorders showed the same correlates. Concerning clinical outcomes, the presence of psychotic symptoms, hallucinations and delusional symptoms was associated with all non-psychotic disorders, i.e., bipolar, depressive, alcohol use, generalized anxiety, social phobia, panic and post-traumatic stress disorders and dysthymia (except dysthymia, which was not associated with hallucinations).
CONCLUSIONS
Our results indicate that psychotic symptoms are associated with broad psychopathologies and support the continuum model of psychosis.
背景
我们旨在探讨大样本一般人群中精神病症状的社会人口学和精神病理学相关性。
方法
法国精神卫生综合人群横断面调查使用 Mini 国际神经精神访谈对 38694 名个体进行访谈。我们寻找了一生中存在精神病症状与社会人口学特征（包括三代以上移民身份）和临床特征之间的关联。然后，我们仅关注幻觉、妄想症状以及两者同时存在的情况。为了检验精神病连续性假说，我们比较了与社会人口学特征的关联与特征性精神病障碍的关联。
结果
我们发现，22.3%的人群报告了精神病症状，但没有精神病障碍，其中 5.7%报告了幻觉，20.5%报告了妄想症状，4.0%报告了两者同时存在，2.8%报告了特征性精神病障碍。存在精神病症状与年龄较小、移民身份（三代以上）、中等教育程度、低收入水平以及未婚和分居的婚姻状况有关。幻觉、妄想症状和两者同时存在的情况表现出相同的相关性，而幻觉还与小学教育程度有关。特征性精神病障碍表现出相同的相关性。就临床结果而言，精神病症状、幻觉和妄想症状的存在与所有非精神病障碍有关，即双相情感障碍、抑郁障碍、酒精使用障碍、广泛性焦虑障碍、社交恐惧症、惊恐障碍和创伤后应激障碍以及心境恶劣障碍（心境恶劣障碍与幻觉无关）。
结论
我们的结果表明，精神病症状与广泛的精神病理学有关，并支持精神病的连续性模型。
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