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血流导向支架治疗颈内动脉夹层及假性动脉瘤:文献综述与病例报告

Flow-diverting Stent in the Treatment of Cervical Carotid Dissection and Pseudoaneurysm: Review of Literature and Case Report.

作者信息

Baptista-Sincos Anna Paula Weinhardt, Simplício Aline Bigatão, Sincos Igor Rafael, Leaderman Alex, Neto Fernando Saliture, Moraes Adjaldes, Aun Ricardo

机构信息

Department of Surgery, Vascular and Endovascular Division of Albert Einstein Hospital, São Paulo, SP, Brazil.

Department of Surgery, Vascular and Endovascular Division of Albert Einstein Hospital, São Paulo, SP, Brazil.

出版信息

Ann Vasc Surg. 2018 Jan;46:372-379. doi: 10.1016/j.avsg.2017.06.151. Epub 2017 Jul 6.

Abstract

BACKGROUND

The endovascular technique has been recommended over the past few years to extracranial carotid dissection and pseudoaneurysm with promising results, especially after medical therapy failure. Flow-diverting stents are an alternative for complex cases. These stents have proven to be effective treatment devices for intracranial aneurysms.

METHODS

The reference list of Pham's systematic review, published in 2011, and Seward's literature review, published in 2015, was considered, as well as all new articles with eligible features. Search was conducted on specific databases: MEDLINE and Literatura Latino-Americana e do Caribe em Ciências da Saúde.

RESULTS

For carotid dissection and pseudoaneurysm, our review yielded 3 published articles including 12 patients. The technical success rate of flow-diverting stent was 100% with no procedural complication described. Mean clinical follow-up was 27.2 months (range 5-48), and in 5 months' angiographic follow-up, all lesions had healed. No new neurological events were reported during the clinical follow-up.

CONCLUSIONS

Flow diverter stent use on intracranial and peripheral vascular surgery demonstrates satisfactory initial results, but it is still under investigation. There are very few cases treated till now and the initial results with flow-diverting stents to cervical carotid dissection are promising. In well-selected cases, where simple embolization or conventional stent is not appropriate, this technic may be considered.

摘要

背景

在过去几年中,血管内技术已被推荐用于治疗颅外颈动脉夹层和假性动脉瘤,并取得了令人鼓舞的结果,尤其是在药物治疗失败后。血流导向支架是复杂病例的一种替代选择。这些支架已被证明是治疗颅内动脉瘤的有效装置。

方法

参考了2011年发表的Pham的系统评价以及2015年发表的Seward的文献综述的参考文献列表,以及所有具有符合条件特征的新文章。在特定数据库进行搜索:MEDLINE和拉丁美洲及加勒比卫生科学文献数据库。

结果

对于颈动脉夹层和假性动脉瘤,我们的综述产生了3篇已发表文章,包括12例患者。血流导向支架的技术成功率为100%,未描述有手术并发症。平均临床随访时间为27.2个月(范围5 - 48个月),在5个月的血管造影随访中,所有病变均已愈合。临床随访期间未报告新的神经事件。

结论

血流导向支架在颅内和外周血管手术中的应用显示出令人满意的初步结果,但仍在研究中。到目前为止治疗的病例非常少,血流导向支架治疗颈内动脉夹层的初步结果很有前景。在精心挑选的、简单栓塞或传统支架不合适的病例中,可以考虑这种技术。

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