QT间期延长。

QT interval prolongation.

作者信息

Scott J L, Walls R M

出版信息

J Emerg Med. 1985;3(3):221-5. doi: 10.1016/0736-4679(85)90076-9.

Abstract

The QT interval is a function of ventricular repolarization time and is measured from the onset of the QRS complex to the end of the T wave. The length of this interval is inversely related to heart rate. A prolonged QT interval is most often secondary to the use of Type I antidysrhythmic medications (quinidine, procainamide). It is also associated with phenothiazines, organophosphates, hypocalcemia, liquid protein diets and the congenital long QT syndromes. QT prolongation is associated with a variety of ventricular dysrhythmias, most characteristically Torsades des pointes. Treatment consists of correction of the underlying metabolic disorder or discontinuation of the offending medication.

摘要

QT间期是心室复极时间的函数，从QRS波群起点测量至T波终点。该间期的长度与心率呈负相关。QT间期延长最常见于使用I类抗心律失常药物（奎尼丁、普鲁卡因胺）之后。它还与吩噻嗪类、有机磷、低钙血症、流质蛋白饮食以及先天性长QT综合征有关。QT间期延长与多种室性心律失常相关，最典型的是尖端扭转型室速。治疗包括纠正潜在的代谢紊乱或停用引起问题的药物。