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QT间期延长。

QT interval prolongation.

作者信息

Scott J L, Walls R M

出版信息

J Emerg Med. 1985;3(3):221-5. doi: 10.1016/0736-4679(85)90076-9.

DOI:10.1016/0736-4679(85)90076-9
PMID:2869081
Abstract

The QT interval is a function of ventricular repolarization time and is measured from the onset of the QRS complex to the end of the T wave. The length of this interval is inversely related to heart rate. A prolonged QT interval is most often secondary to the use of Type I antidysrhythmic medications (quinidine, procainamide). It is also associated with phenothiazines, organophosphates, hypocalcemia, liquid protein diets and the congenital long QT syndromes. QT prolongation is associated with a variety of ventricular dysrhythmias, most characteristically Torsades des pointes. Treatment consists of correction of the underlying metabolic disorder or discontinuation of the offending medication.

摘要

QT间期是心室复极时间的函数,从QRS波群起点测量至T波终点。该间期的长度与心率呈负相关。QT间期延长最常见于使用I类抗心律失常药物(奎尼丁、普鲁卡因胺)之后。它还与吩噻嗪类、有机磷、低钙血症、流质蛋白饮食以及先天性长QT综合征有关。QT间期延长与多种室性心律失常相关,最典型的是尖端扭转型室速。治疗包括纠正潜在的代谢紊乱或停用引起问题的药物。

相似文献

1
QT interval prolongation.QT间期延长。
J Emerg Med. 1985;3(3):221-5. doi: 10.1016/0736-4679(85)90076-9.
2
Electrocardiographic implications of the prolonged QT interval.心电图 QT 间期延长的意义。
Am J Emerg Med. 2013 May;31(5):866-71. doi: 10.1016/j.ajem.2012.12.013. Epub 2013 Apr 18.
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Pharmacologic agents associated with QT interval prolongation.与QT间期延长相关的药物制剂。
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Mechanism of ventricular arrhythmias in the long QT syndrome: on hermeneutics.长QT综合征中心室心律失常的机制:论诠释学
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The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications.作为药理学靶点的心脏hERG/IKr钾通道:结构、功能、调节及临床应用
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Effects of β-blockers on ventricular repolarization documented by 24-hour electrocardiography in long QT syndrome type 2.24小时心电图记录的β受体阻滞剂对2型长QT综合征心室复极的影响。
Heart Rhythm. 2022 Sep;19(9):1491-1498. doi: 10.1016/j.hrthm.2022.04.028. Epub 2022 May 4.
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Torsades de pointes and long QT syndromes.尖端扭转型室速与长QT综合征。
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8
Long QT: good, bad or indifferent?长QT间期:有益、有害还是无关紧要?
J Am Coll Cardiol. 1984 Aug;4(2):398-413. doi: 10.1016/s0735-1097(84)80232-6.
9
[Current principles of the treatment of prolonged QT interval syndrome].[长QT间期综合征的当前治疗原则]
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10
[QT prolongation and torsade de pointes tachycardia during therapy with maprotiline. Differential diagnostic and therapeutic aspects].[米安色林治疗期间的QT间期延长和尖端扭转型室性心动过速。鉴别诊断和治疗方面]
Dtsch Med Wochenschr. 2001 Dec 7;126(49):1396-400. doi: 10.1055/s-2001-18880.

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2
Association Between Particulate Air Pollution and QT Interval Duration in an Elderly Cohort.老年队列中细颗粒物空气污染与QT间期时长的关联
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Association between low-level environmental arsenic exposure and QT interval duration in a general population study.
一项普通人群研究中低水平环境砷暴露与QT间期持续时间的关联。
Am J Epidemiol. 2009 Sep 15;170(6):739-46. doi: 10.1093/aje/kwp191. Epub 2009 Aug 21.
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Antipsychotic agents and QT changes.抗精神病药物与QT间期变化
J Psychiatry Neurosci. 2000 Mar;25(2):154-60.