Aquino-Cortez A, Pinheiro B Q, Silva Hvr, Lima Dbc, Silva Tfp, Souza M B, Viana D A, Xavier Júnior Faf, Evangelista Jsam, Brandão F Z, Silva Ldm
Faculty of Veterinary Medicine, State University of Ceará, Fortaleza, Brazil.
Faculty of Veterinary Medicine, Fluminense Federal University, Niterói, Brazil.
Reprod Domest Anim. 2017 Dec;52(6):998-1003. doi: 10.1111/rda.13009. Epub 2017 Jul 9.
Prostatomegaly is a common finding in older non-neutered dogs. This study compared the serum testosterone, sperm quality and characteristics of the prostatic fraction between healthy dogs and dogs with prostatomegaly. Blood samples of ten dogs (five dogs from each group) were taken for serum testosterone measurement. Sperm motility, vigour, concentration, viability, membrane functionality and morphology were analysed in sperm-rich fraction. Osmolality, pH, cell types, and albumin, haemoglobin, acid phosphatase, alkaline phosphatase, glucose, triglycerides, cholesterol, calcium, phosphorus, magnesium and chloride were analysed in prostatic fraction. Dogs with prostatomegaly have the lowest sperm motility, vigour, concentration and functional membrane. Dogs with prostatomegaly have the highest glucose, triglycerides and cholesterol. Glucose was the only constituent positively correlated with serum testosterone and prostate volume. It can be concluded that dogs with prostatomegaly have poorer sperm quality, and glucose, triglycerides and cholesterol in prostatic fraction can be used as prostatomegaly biomarkers.
前列腺肿大在未绝育的老年犬中是常见现象。本研究比较了健康犬和患有前列腺肿大的犬的血清睾酮、精子质量以及前列腺部分的特征。采集了十只犬（每组五只）的血样用于测定血清睾酮。对富含精子的部分进行精子活力、活力、浓度、存活率、膜功能和形态分析。对前列腺部分进行渗透压、pH值、细胞类型以及白蛋白、血红蛋白、酸性磷酸酶、碱性磷酸酶、葡萄糖、甘油三酯、胆固醇、钙、磷、镁和氯的分析。患有前列腺肿大的犬精子活力、活力、浓度和功能膜最低。患有前列腺肿大的犬葡萄糖、甘油三酯和胆固醇含量最高。葡萄糖是唯一与血清睾酮和前列腺体积呈正相关的成分。可以得出结论，患有前列腺肿大的犬精子质量较差，前列腺部分的葡萄糖、甘油三酯和胆固醇可作为前列腺肿大的生物标志物。
