Kashfi Karl, Al-Khalil Kareem, Hou Jiancheng, Fang Dan, Anderson Ron, Rajmohan Ravi, Syapin Peter, O'Boyle Michael W
a Department of Pharmacology and Neuroscience , Texas Tech Health Sciences Center , Lubbock , TX , USA.
b Department of Human Development and Family Studies , Texas Tech University , Lubbock , TX , USA.
Neurocase. 2017 Jun-Aug;23(3-4):179-186. doi: 10.1080/13554794.2017.1347264. Epub 2017 Jul 10.
The current study used diffusion tensor imaging to examine patterns/degree of brain connectivity in 12 college-aged binge drinking (BD) and 12 moderate drinking individuals. Voxel-level and region-of-interest analyses revealed increased connectivity of the BD brain in the right corona radiata, right external capsule, and both the right and left cingulum. Also, fractional anisotropy and axial diffusivity values of these regions correlated with a number of drinking behaviors of the BD as well as both groups combined. It is hypothesized that increased connectivity in the BD may produce difficulties with regulatory control, contributing to their propensity to binge.
当前研究使用扩散张量成像技术,对12名大学年龄的暴饮者(BD)和12名适度饮酒者的大脑连接模式/程度进行了检查。体素水平和感兴趣区域分析显示,BD组大脑右侧放射冠、右侧外囊以及左右扣带束的连接性增强。此外,这些区域的分数各向异性和轴向扩散率值与BD组以及两组合并后的多种饮酒行为相关。据推测,BD组大脑连接性增强可能会导致调节控制困难,从而导致他们暴饮的倾向。