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基于先验知识和相位对称性的超声图像中手指伸肌腱的新型主动轮廓方法

A New Active Contours Approach for Finger Extensor Tendon Segmentation in Ultrasound Images Using Prior Knowledge and Phase Symmetry.

出版信息

IEEE J Biomed Health Inform. 2018 Jul;22(4):1261-1268. doi: 10.1109/JBHI.2017.2723819. Epub 2017 Jul 5.

DOI:10.1109/JBHI.2017.2723819
PMID:28693000
Abstract

This work proposes a new approach for the segmentation of the extensor tendon in ultrasound images of the second metacarpophalangeal joint (MCPJ). The MCPJ is known to be frequently involved in early stages of rheumatic diseases like rheumatoid arthritis. The early detection and follow up of these diseases is important to start and adapt the treatments properly and, in that way, preventing irreversible damage of the joints. This work relies on an active contours framework, preceded by a phase symmetry preprocessing and with prior knowledge energies, to automatically identify the extensor tendon. Active contours methods are widely used in ultrasound images because of their robustness to speckle noise and ability to join unconnected smaller regions into a coherent shape. The tendon is formulated as a line so open ended active contours were used. Phase symmetry highlights the tendon, by setting a proper scale range and angle span. The distance between structures and the tendon slope were also included to enforce the model based on anatomical characteristics. And finally, the concavity measures were used because, given the anatomy of the finger, we know that the tendon line should have less than two concavities. To solve the active contours energy minimization a genetic algorithm approach was used. Several energy metric configurations were compared using the modified Hausdorff distance and results showed that this segmentation is not only possible, but exhibits errors smaller than 0.5 mm with a confidence of 95% with the phase symmetry preprocessing and energies based on the line neighborhood, area ratio, slope, and concavity measurements.

摘要

本研究提出了一种新的方法,用于分割第二掌指关节(MCPJ)的超声图像中的伸肌腱。众所周知,MCPJ 常涉及类风湿关节炎等风湿性疾病的早期阶段。早期发现和跟踪这些疾病对于适当开始和调整治疗非常重要,从而防止关节的不可逆转损伤。该研究依赖于主动轮廓框架,之前进行了相位对称预处理,并具有先验知识能量,以自动识别伸肌腱。主动轮廓方法因其对斑点噪声的鲁棒性和将未连接的较小区域连接成连贯形状的能力而广泛用于超声图像。肌腱被表示为一条线,因此使用了开口主动轮廓。相位对称通过设置适当的比例范围和角度跨度来突出肌腱。还包括结构之间的距离和肌腱斜率,以基于解剖特征来加强模型。最后,使用凹度度量,因为考虑到手的解剖结构,我们知道肌腱线应该少于两个凹口。为了解决主动轮廓能量最小化问题,使用了遗传算法方法。使用改进的 Hausdorff 距离比较了几种能量度量配置,结果表明,这种分割不仅是可能的,而且在相位对称预处理和基于线邻域、面积比、斜率和凹度测量的能量的情况下,其误差小于 0.5mm,置信度为 95%。

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