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Polycystic ovary syndrome induced by exposure to testosterone propionate and effects of sympathectomy on the persistence of the syndrome.

作者信息

Morales-Ledesma Leticia, Díaz Ramos Juan Antonio, Trujillo Hernández Angélica

机构信息

Biology of Reproduction Research Unit, Physiology of Reproduction Laboratory, Facultad de Estudios Superiores Zaragoza, UNAM, AP 9-020, CP 15000, México, D. F, México.

Benemérita Universidad Autónoma de Puebla, Facultad de Ciencias Biológicas, Edificio BIO1, Ciudad Universitaria, Boulevard Valsequillo y Avenida San Claudio S/N. C.P, 72570, Puebla, Puebla, México.

出版信息

Reprod Biol Endocrinol. 2017 Jul 10;15(1):50. doi: 10.1186/s12958-017-0267-0.

DOI:10.1186/s12958-017-0267-0
PMID:28693534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5504549/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d118/5504549/d1ce40a86b12/12958_2017_267_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d118/5504549/a7d41b7f20ed/12958_2017_267_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d118/5504549/d9a04d596929/12958_2017_267_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d118/5504549/3690b2f4955b/12958_2017_267_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d118/5504549/d1ce40a86b12/12958_2017_267_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d118/5504549/a7d41b7f20ed/12958_2017_267_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d118/5504549/d9a04d596929/12958_2017_267_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d118/5504549/3690b2f4955b/12958_2017_267_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d118/5504549/d1ce40a86b12/12958_2017_267_Fig4_HTML.jpg

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本文引用的文献

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Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome.神经内分泌雄激素作用是多囊卵巢综合征发生的关键卵巢外中介因素。
Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3334-E3343. doi: 10.1073/pnas.1616467114. Epub 2017 Mar 20.
2
Ovarian follicular dynamics after aromatizable or non aromatizable neonatal androgenization.可芳香化或不可芳香化的新生期雄激素化后的卵巢卵泡动力学
J Mol Histol. 2016 Oct;47(5):491-501. doi: 10.1007/s10735-016-9692-1. Epub 2016 Aug 19.
3
The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited.
食欲素拮抗作用和 P 物质:对 Wistar 大鼠多囊卵巢综合征的影响及相互作用。
J Ovarian Res. 2023 May 5;16(1):89. doi: 10.1186/s13048-023-01168-4.
4
Pharmacological sympathetic denervation prevents the development of polycystic ovarian syndrome in rats injected with estradiol valerate.药物性交感神经切断术可预防戊酸雌二醇注射诱导的大鼠多囊卵巢综合征的发生。
Reprod Biol Endocrinol. 2018 Sep 7;16(1):86. doi: 10.1186/s12958-018-0400-8.
多囊卵巢综合征(PCOS)的发病机制:重新审视PCOS作为功能性卵巢雄激素过多症的假说
Endocr Rev. 2016 Oct;37(5):467-520. doi: 10.1210/er.2015-1104. Epub 2016 Jul 26.
4
Neonatal testosterone exposure induces early development of follicular cysts followed by sympathetic ovarian hyperinnervation.
Reprod Fertil Dev. 2015 May 20. doi: 10.1071/RD14460.
5
Neonatal androgenization-induced early endocrine-metabolic and ovary misprogramming in the female rat.新生雄性化诱导的雌性大鼠早期内分泌代谢和卵巢编程异常。
Life Sci. 2015 Jun 1;130:66-72. doi: 10.1016/j.lfs.2015.03.008. Epub 2015 Mar 26.
6
Sympathetic regulation of estradiol secretion from the ovary.卵巢雌二醇分泌的交感神经调节。
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