Akahane Mizuho, Nakashima Masakazu, Sakamoto Hiromasa, Aoyama Teruyoshi, Kawai Jun
The Department of Urology, Kansai Electric Power Hospital.
The Department of Pathology, Kansai Electric Power Hospital.
Hinyokika Kiyo. 2017 Jun;63(6):239-243. doi: 10.14989/ActaUrolJap_63_6_239.
Carcinoma of the collecting ductsof Bellini isa rare histological subtype of renal cell carcinoma and mostly has unfavorable prognosis. Radical nephrectomy is generally chosen for the 1st line treatment but therapeutic approaches for the metastasis/recurrence have not been established. We report a case of carcinoma of collecting ducts of Bellini in a patient receiving hemodialysis treated with temsirolimus. A 62- year-old man receiving hemodialysis was admitted to our hospital with drug-resistant anemia and high-grade cyclic fever. Computed tomography revealed the right renal tumor and multiple metastatic lung tumors. Open radical nephrectomy wasperformed. Pathological findingswere compatible with carcinoma of the collecting ducts of Bellini. He was given weekly temsirolimus treatment. The disease progressed modestly but kept the stable disease (SD) status for six months. He died of the cancer 11 months after the initial diagnosis.
贝氏集合管癌是肾细胞癌中一种罕见的组织学亚型,预后大多不良。根治性肾切除术通常被选为一线治疗方法,但针对转移/复发的治疗方案尚未确立。我们报告了一例接受替西罗莫司治疗的血液透析患者发生贝氏集合管癌的病例。一名62岁接受血液透析的男性因耐药性贫血和高热入院。计算机断层扫描显示右肾肿瘤和多个肺转移瘤。实施了开放性根治性肾切除术。病理结果与贝氏集合管癌相符。给予他每周一次的替西罗莫司治疗。疾病进展较为缓慢,但保持稳定疾病(SD)状态达6个月。他在初次诊断后11个月死于癌症。