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脊髓血管脂肪瘤:一个令人困惑的病例及对罕见实体的综述。

Spinal angiolipomas: A puzzling case and review of a rare entity.

作者信息

Shweikeh Faris, Sangtani Ajleeta, Steinmetz Michael P, Zahos Peter, Chopko Bohdan

机构信息

Summa Health System, Northeast Ohio Medical University, Rootstown, USA.

College of Medicine, Northeast Ohio Medical University, Rootstown, USA.

出版信息

J Craniovertebr Junction Spine. 2017 Apr-Jun;8(2):91-96. doi: 10.4103/jcvjs.JCVJS_23_17.

Abstract

Patients with spinal epidural abscesses (SEAs) may have a variable presentation. Such an infection has a typical appearance on magnetic resonance imaging (MRI) and enhances with gadolinium. We present a case that was a diagnostic challenge where pre- and intra-operative findings resulted in conflicting impressions. The mimicker was a spinal angiolipoma (SAL). The authors then provide a thorough review of this rare spinal neoplasm. A 55-year-old man presented with back pain, paresis, paresthesia, and urinary retention. MRI was indicative of a longitudinal epidural thoracic mass with a signal homogeneous to nearby fat, curvilinear vessels, and lack of enhancement. Although at emergent surgery, the lesion was found to contain abundant purulent material. Microbiology was positive for methicillin-resistant and consistent with SEA without evidence of neoplasia. While the imaging features were suggestive of an angiolipoma, the findings at surgery made SEA more likely, which were validated histopathologically. The diagnosis of SEA is often clear-cut, and the literature has reported only a few instances in which it masqueraded as another process such as lymphoma or myelitis. The case highlights SEA masquerading as an angiolipoma, and further demonstrates to clinicians that obtaining tissue diagnosis plays a crucial role diagnostically and therapeutically. SALs, on the other hand, are slow-growing tumors that can be infiltrating or noninfiltrating. They typically present with chronic symptoms and T1-MRI shows an inhomogeneous picture. Complete surgical excision is standard of care and patients tend to do well afterward.

摘要

脊髓硬膜外脓肿(SEA)患者的临床表现可能多种多样。这种感染在磁共振成像(MRI)上有典型表现,注射钆剂后会强化。我们报告一例诊断具有挑战性的病例,术前和术中发现导致了相互矛盾的判断。造成误诊的疾病是脊髓血管脂肪瘤(SAL)。作者随后对这种罕见的脊髓肿瘤进行了全面综述。一名55岁男性出现背痛、轻瘫、感觉异常和尿潴留。MRI显示胸段硬膜外有一纵向肿块,信号与附近脂肪均匀一致,有曲线状血管,且无强化。尽管在急诊手术中发现病变含有大量脓性物质。微生物学检查显示耐甲氧西林阳性,符合SEA,无肿瘤形成证据。虽然影像学特征提示为血管脂肪瘤,但手术结果使SEA的可能性更大,这在组织病理学上得到了证实。SEA的诊断通常很明确,文献中仅报道了少数几例其伪装成其他疾病(如淋巴瘤或脊髓炎)的情况。该病例突出了SEA伪装成血管脂肪瘤的情况,并进一步向临床医生表明,获得组织诊断在诊断和治疗中起着至关重要的作用。另一方面,SAL是生长缓慢的肿瘤,可呈浸润性或非浸润性。它们通常表现为慢性症状,T1加权MRI显示图像不均匀。完整的手术切除是标准治疗方法,患者术后往往恢复良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f30/5490357/13e5cad6190e/JCVJS-8-91-g001.jpg

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