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飞秒激光辅助Descemet膜剥离自动内皮角膜移植术的结果

Results of Femtosecond Laser-Assisted Descemet Stripping Automated Endothelial Keratoplasty.

作者信息

Hosny Mohamed H, Marrie Ayah, Karim Sidky M, GamalEldin Sherif, Salem Mohsen

机构信息

Department of Ophthalmology, Cairo University, Cairo, Egypt.

出版信息

J Ophthalmol. 2017;2017:8984367. doi: 10.1155/2017/8984367. Epub 2017 Jun 11.

DOI:10.1155/2017/8984367
PMID:28695004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5485480/
Abstract

PURPOSE

To evaluate femtosecond laser in DSAEK surgery as an improvement to manual DSAEK.

SETTINGS

Department of Ophthalmology, Cairo University.

DESIGN

A retrospective observational clinical study.

METHODS

20 eyes with SBK and Fuchs' dystrophy underwent a Femto-assisted DSAEK by laser cutting of two matching posterior stromal discs in the recipient and donor corneas and then fitting the donor disc in the posterior corneal defect of the recipient using Busin's glide or Terry forceps.

RESULTS

Corneal thickness decreased significantly from a mean of 900-micron preoperative values (900.7 m) to 562 m postoperatively. Evidence of side healing was documented by OCT. One patient had a double AC, one patient had an air interface entrapment "Double Bubble," one patient had a fungal infection and was treated by a therapeutic penetrating keratoplasty, and one patient had a CMO.

CONCLUSION

Femtolaser-assisted DSAEK may be superior to manual techniques as it offers better centration, thinner graft/host complex, earlier corneal detergecense, and stronger healing. This study was registered at Researchregistry.com with a UID: researchregistry2274.

摘要

目的

评估飞秒激光在角膜内皮移植术（DSAEK）中对传统手动DSAEK手术的改进效果。

地点

开罗大学眼科。

设计

一项回顾性观察性临床研究。

方法

对20例患有表层角膜刀角膜磨镶术（SBK）和富克斯营养不良的患者行飞秒激光辅助的DSAEK手术，通过激光切割受体和供体角膜中两个匹配的后基质盘，然后使用布辛滑行器或特里镊子将供体盘植入受体角膜的后角膜缺损处。

结果

角膜厚度从术前平均900微米（900.7微米）显著降至术后的562微米。光学相干断层扫描（OCT）记录了边缘愈合的证据。1例患者出现前房积血，1例患者出现空气界面嵌顿（“双泡”），1例患者发生真菌感染并接受了治疗性穿透性角膜移植术，1例患者发生角膜瓣下上皮植入（CMO）。

结论

飞秒激光辅助的DSAEK可能优于传统手动技术，因为它具有更好的对中、更薄的移植片/宿主复合体、更早的角膜清洁和更强的愈合能力。本研究已在Researchregistry.com注册，唯一识别码为：researchregistry2274。

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Arch Soc Esp Oftalmol. 2015 Apr;90(4):164-79. doi: 10.1016/j.oftal.2014.09.002. Epub 2014 Nov 15.
3
Endothelial keratoplasty versus penetrating keratoplasty for Fuchs endothelial dystrophy.
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Cochrane Database Syst Rev. 2014 Feb 14;2014(2):CD008420. doi: 10.1002/14651858.CD008420.pub3.
4
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