印度南部泰米尔纳德邦国家艾滋病项目下接受抗逆转录病毒治疗前护理的儿童失访情况。
Loss to follow-up among children in pre-ART care under the National AIDS Programme, Tamil Nadu, South India.
作者信息
Devi N P, Kumar A M V, Chinnakali P, Rajendran M, Valan A S, Rewari B B, Swaminathan S
机构信息
National Institute for Research in Tuberculosis, Madurai, India.
International Union Against Tuberculosis and Lung Disease, (The Union) Paris, France.
出版信息
Public Health Action. 2017 Jun 21;7(2):90-94. doi: 10.5588/pha.16.0112.
Children aged <15 years constitute 7% of all people living with the human immunodeficiency virus (HIV) in India. A previous study from an antiretroviral therapy (ART) centre in south India reported 82% loss to follow-up (LTFU) among children in pre-ART care (2006-2011). To assess the proportion of LTFU within 1 year of registration among HIV-infected children (aged < 15 years) registered in all 43 ART centres in the state of Tamil Nadu, India, during the year 2012. This was a retrospective cohort study involving a review of programme records. Of 656 children registered for HIV care, 20 (3%) were not assessed for ART eligibility. Of those remaining, 226 (36%) were not ART eligible and entered pre-ART care. Among these, at 1 year of registration, 50 (22%) were LTFU, 40 (18%) were transferred out and 136 (60%) were retained in care at the same centre. The child's age, sex, World Health Organization stage or occurrence of opportunistic infection were not associated with LTFU. One in five children registered under pre-ART care were lost to follow-up. Stronger measures to prevent LTFU and reinforce retrieval actions are necessary in the existing National HIV Programme.
15岁以下儿童占印度所有人类免疫缺陷病毒（HIV）感染者的7%。印度南部一家抗逆转录病毒疗法（ART）中心之前的一项研究报告称，在接受ART治疗前护理的儿童中（2006 - 2011年），随访失访率（LTFU）为82%。为评估2012年印度泰米尔纳德邦所有43家ART中心登记的HIV感染儿童（15岁以下）登记后1年内的LTFU比例。这是一项回顾性队列研究，涉及对项目记录的审查。在656名登记接受HIV护理的儿童中，20名（3%）未评估ART资格。在其余儿童中，226名（36%）不符合ART资格并进入ART治疗前护理。其中，登记1年后，50名（22%）失访，40名（18%）转出，136名（60%）仍在同一中心接受护理。儿童的年龄、性别、世界卫生组织分期或机会性感染的发生与LTFU无关。接受ART治疗前护理登记的儿童中有五分之一失访。在现有的国家HIV项目中，需要采取更强有力的措施来预防LTFU并加强找回行动。
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