Van de Wiele Christophe, Verstraete Koenraad, Bourgeois Sophie, Maes Alex
Department of Imaging and Pathology, University of Leuven, Belgium.
Hell J Nucl Med. 2017 May-Aug;20(2):182-183. doi: 10.1967/s002449910563. Epub 2017 Jul 12.
We report our fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (FFDG PET/CT) findings in a 51 years old female presenting with B symptoms, respectively fever, night sweats and malaise, that underwent an F-FDG PET/CT examination to exclude underlying lymphomatous disease. Whereas F-FDG PET scan findings were negative, CT put to evidence the presence of multiple small lesions suggestive for multifocal hamartoma. On a subsequently performed magnetic resonance imaging (MRI) of the spleen, multiple infracentimetric foci were visualized displaying characteristic findings for hamartoma. During a follow-up period of two years no change in size or characteristics of these lesions occurred.
The normal :F-FDG PET/CT findings suggested that, at least in this patient, splenic hamartoma may display a similar :F-FDG avidity when compared to normal splenic tissue. Alternatively, due to the infra-centrimeric size of the hamartoma and spill-over from :F-FDG activity from neighbouring normal tissue, the true F-FDG avidity of the hamartomas present might also be overestimated.
我们报告了一名51岁女性的氟-18-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（F-FDG PET/CT）检查结果。该女性有B症状，即发热、盗汗和乏力，接受F-FDG PET/CT检查以排除潜在的淋巴瘤疾病。F-FDG PET扫描结果为阴性，但CT显示存在多个提示多灶性错构瘤的小病变。随后对脾脏进行的磁共振成像（MRI）显示，多个小于1厘米的病灶具有错构瘤的特征性表现。在两年的随访期内，这些病变的大小和特征没有变化。
正常的F-FDG PET/CT结果表明，至少在该患者中，脾脏错构瘤与正常脾脏组织相比可能表现出相似的F-FDG摄取。或者，由于错构瘤小于1厘米的大小以及邻近正常组织F-FDG活性的溢出，所存在的错构瘤的真正F-FDG摄取也可能被高估。
