RA 让道以实现高敏锐度视觉。

RA Gets Out of the Way to Allow High-Acuity Vision.

机构信息

Cellular Neurobiology Research Unit, Montreal Clinical Research Institute (IRCM), Montreal, QC H2W 1R7, Canada; Integrated Program in Neuroscience, McGill University, Montreal, QC H3A 2B4, Canada.

Cellular Neurobiology Research Unit, Montreal Clinical Research Institute (IRCM), Montreal, QC H2W 1R7, Canada; Integrated Program in Neuroscience, McGill University, Montreal, QC H3A 2B4, Canada; Department of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada.

出版信息

Dev Cell. 2017 Jul 10;42(1):3-5. doi: 10.1016/j.devcel.2017.06.015.

DOI:10.1016/j.devcel.2017.06.015

PMID:28697330

Abstract

Specialized areas in the vertebrate retina are critical for high-acuity vision, yet the molecular mechanisms driving the development of high-acuity areas (HAAs) remain largely unknown. In Developmental Cell, da Silva and Cepko (2017) show that restricted degradation of retinoic acid and elevated FGF8 signaling give rise to the chick HAA.

摘要

脊椎动物视网膜中的特定区域对高清晰度视觉至关重要，但驱动高清晰度区域（HAA）发育的分子机制在很大程度上仍不清楚。在《发育细胞》杂志上，da Silva 和 Cepko（2017）的研究表明，视黄酸的限制降解和 FGF8 信号的升高导致了小鸡的 HAA。