Szabó L, Matkovics B, Barabás K, Oroszlán G
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1986;83(1):149-53. doi: 10.1016/0742-8413(86)90028-9.
It was demonstrated that cysteine and D-penicillamine are able to replace reduced glutathione to some extent in the glutathione peroxidase reaction. An in vivo study was made of the role played by--SH compounds in the antioxidant enzyme system involved in the detoxication of the LD50 of paraquat (PQ), and hence of their role in the detoxication of PQ. The effectiveness was D-PA greater than GSH greater then Cys in the liver and GSH greater than Cys greater than D-PA in the lung.
已证明半胱氨酸和D-青霉胺在谷胱甘肽过氧化物酶反应中能够在一定程度上替代还原型谷胱甘肽。对参与百草枯（PQ）半数致死量解毒的抗氧化酶系统中-SH化合物所起的作用进行了体内研究，从而研究它们在PQ解毒中的作用。在肝脏中，有效性为D-PA＞GSH＞Cys，在肺中为GSH＞Cys＞D-PA。
