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胎儿巨膀胱:机构经验与结局

Fetal megacystis: Institutional experience and outcomes.

作者信息

Taghavi Kiarash, Sharpe Caitlin, Stringer Mark D, Zuccollo Jane, Marlow Jay

机构信息

Department of Paediatric Surgery, Wellington Children's Hospital, Wellington, New Zealand.

Department of Paediatrics and Child Health, University of Otago, Wellington, New Zealand.

出版信息

Aust N Z J Obstet Gynaecol. 2017 Dec;57(6):636-642. doi: 10.1111/ajo.12655. Epub 2017 Jul 12.

Abstract

BACKGROUND

Fetal megacystis is a sonographic feature that may be indicative of several underlying pathologies. Despite advances in diagnosis and management, the overall prognosis of affected fetuses remains poor and about 50% of such pregnancies are terminated.

AIMS

To define the frequency, management, survival and renal outcomes of fetal megacystis over nine years at Wellington Hospital, New Zealand.

MATERIALS AND METHODS

A nine-year retrospective review of fetuses with an antenatal diagnosis of megacystis was undertaken.

RESULTS

Sixteen cases were identified (nine live births, five terminations and two perinatal deaths). This gives an observed frequency of one per 940 fetuses scanned. Two-thirds of the live births have survived and been followed for a mean of 5.3 years. None have required renal dialysis or transplantation to date.

CONCLUSIONS

The current series contributes to our knowledge of fetal megacystis and helps to inform antenatal counselling. Improved prognostic criteria are urgently required to accurately differentiate between fetuses with favourable versus poor outcomes.

摘要

背景

胎儿巨膀胱是一种超声特征,可能提示多种潜在病理情况。尽管在诊断和管理方面取得了进展,但受影响胎儿的总体预后仍然很差,约50%的此类妊娠会终止。

目的

确定新西兰惠灵顿医院9年间胎儿巨膀胱的发生率、管理、存活率和肾脏结局。

材料与方法

对产前诊断为巨膀胱的胎儿进行了为期9年的回顾性研究。

结果

共确定16例(9例活产、5例终止妊娠和2例围产期死亡)。观察到的发生率为每940例扫描胎儿中有1例。三分之二的活产儿存活下来,平均随访5.3年。迄今为止,无人需要肾透析或肾移植。

结论

本系列研究有助于我们了解胎儿巨膀胱,并为产前咨询提供参考。迫切需要改进预后标准,以准确区分预后良好和不良的胎儿。

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