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破裂性动脉瘤腔内修复术后血胸的处理

Management of hemothorax after thoracic endovascular aortic repair for ruptured aneurysms.

作者信息

Ju Mila H, Nooromid Michael J, Rodriguez Heron E, Eskandari Mark K

机构信息

Division of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

出版信息

Vascular. 2018 Feb;26(1):39-46. doi: 10.1177/1708538117718109. Epub 2017 Jul 12.

Abstract

Background Thoracic aortic aneurysm rupture is often a fatal condition. Emergent thoracic endovascular aortic repair (TEVAR) has emerged as a suitable treatment option. Unfortunately, respiratory complications from hemothorax continue to be an important cause of morbidity and mortality even after successful management of the aortic rupture. We hypothesize that early hemothorax decompression after TEVAR for ruptured aneurysms decreases the rate of postoperative respiratory complications. Methods Single-center, retrospective eight-year review of ruptured thoracic aneurysms treated with TEVAR. Results Seventeen patients presented with ruptured degenerative thoracic aortic aneurysms, all of which were successfully treated emergently with TEVAR. The mean age was 74 years among the 12 (70.6%) men and 5 (29.4%) women treated. Inpatient and 30-day mortality rates for the entire cohort were both 17.6% (three patients). The 90-day mortality rate was 47.1% (eight patients). Thirty-day morbidities of the entire cohort included stroke ( n = 1, 5.9%), spinal cord ischemia ( n = 3, 17.6%; only one was temporary), cardiac arrest ( n = 4, 23.5%; 3 were fatal), respiratory failure ( n = 5, 29.4%), and renal failure ( n = 5, 29.4%). A large hemothorax was identified in the majority of patients ( n = 14, 82.4%). While six (42.9% of 14) patients had immediate chest tube decompression on the day of index procedure, three (21.4% of 14) patients had decompression on postoperative day 1, 4, and 7, respectively. Although not statistically significant, there were trends toward higher rates of respiratory failure (50.0% vs. 16.7%, P = 0.198) and 90-day mortality (62.5% vs. 33.3%, P = 0.280) for patients with delayed or no hemothorax decompression when compared to patients with immediate hemothorax decompression. Conclusions The morbidity and mortality of ruptured degenerative thoracic aortic aneurysms remains high despite the introduction of TEVAR. In this single-center experience, there was a trend toward decreased respiratory complications and increased survival with early chest decompression of hemothorax after TEVAR.

摘要

背景

胸主动脉瘤破裂通常是一种致命性疾病。急诊胸主动脉腔内修复术(TEVAR)已成为一种合适的治疗选择。不幸的是,即使在成功处理主动脉破裂后,血胸引起的呼吸并发症仍是发病和死亡的重要原因。我们推测,TEVAR治疗破裂动脉瘤后早期进行血胸减压可降低术后呼吸并发症的发生率。

方法

对单中心8年期间接受TEVAR治疗的破裂胸主动脉瘤患者进行回顾性研究。

结果

17例患者患有退行性胸主动脉瘤破裂,均成功接受了急诊TEVAR治疗。接受治疗的12例(70.6%)男性和5例(29.4%)女性的平均年龄为74岁。整个队列的住院死亡率和30天死亡率均为17.6%(3例患者)。90天死亡率为47.1%(8例患者)。整个队列的30天并发症包括中风(n = 1,5.9%)、脊髓缺血(n = 3,17.6%;仅1例为暂时性)、心脏骤停(n = 4,23.5%;3例致命)、呼吸衰竭(n = 5,29.4%)和肾衰竭(n = 5,29.4%)。大多数患者(n = 14,82.4%)发现有大量血胸。在索引手术当天,6例(14例中的42.9%)患者立即进行了胸腔闭式引流减压,3例(14例中的21.4%)患者分别在术后第1天、第4天和第7天进行了减压。与立即进行血胸减压的患者相比,延迟或未进行血胸减压的患者呼吸衰竭发生率(50.0%对16.7%,P = 0.198)和90天死亡率(62.5%对33.3%,P = 0.280)虽无统计学意义,但有升高趋势。

结论

尽管引入了TEVAR,退行性胸主动脉瘤破裂的发病率和死亡率仍然很高。在本单中心经验中,TEVAR术后早期进行血胸胸腔减压有降低呼吸并发症和提高生存率的趋势。

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