畸胎瘤的新发肿瘤：起源于卵巢成熟囊性畸胎瘤的神经节神经瘤。

De Novo Tumors of Teratoma: Ganglioneuroma Arising From a Mature Cystic Teratoma of the Ovary.

作者信息

Coy Shannon, Meserve Emily, Berkowitz Ross, Hirsch Michelle S

机构信息

Departments of Pathology, Women's and Perinatal Pathology Division (S.C., E.M., M.S.H.) Obstetrics and Gynecology, Division of Gynecologic Oncology (R.B.), Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

出版信息

Int J Gynecol Pathol. 2018 May;37(3):296-300. doi: 10.1097/PGP.0000000000000409.

DOI:10.1097/PGP.0000000000000409

PMID:28700440

Abstract

Mature teratomas are the most common ovarian neoplasms, accounting for 40% to 50% of ovarian tumors, and are histologically defined by the presence of multiple lineages of mature differentiated cells derived from one or more of the 3 embryonic germ layers; ectoderm, mesoderm, and endoderm. Neuroectodermal and neural crest differentiation can be observed in mature teratomas, but it is uncommon to find secondary tumors that arise from the neural crest lineage. Herein we report the uncommon finding of a ganglioneuroma arising in a mature cystic teratoma in a 26-yr-old woman.

摘要

成熟畸胎瘤是最常见的卵巢肿瘤，占卵巢肿瘤的40%至50%，在组织学上由源自外胚层、中胚层和内胚层这三个胚胎胚层中一个或多个的多种成熟分化细胞谱系组成来定义。在成熟畸胎瘤中可观察到神经外胚层和神经嵴分化，但源自神经嵴谱系的继发性肿瘤并不常见。在此，我们报告了一名26岁女性的成熟囊性畸胎瘤中出现神经节神经瘤这一罕见发现。