Surintanasarn Atikom, Siralertmukul Krisana, Thamrongananskul Niyom
Department of Prosthodontics, Faculty of Dentistry, Chulalongkorn University.
Metallurgy and Materials Science Research Institute, Chulalongkorn University.
Dent Mater J. 2017 Nov 29;36(6):706-713. doi: 10.4012/dmj.2016-369. Epub 2017 Jul 12.
This study evaluated the effect of different types of filler in a resin-based pit and fissure sealant on fluoride release, recharge, and lactic acid neutralization. Resin-based sealant was incorporated with 5% w/w of the following fillers: calcium aluminate cement (CAC), synthesized mesoporous silica (SI), a CAC and SI mixture (CAC+SI), glass-ionomer powder (GIC), and acetic acid-treated GIC (GICA). Sealant without filler served as control. The samples were immersed in deionized water or a lactic acid solution and the concentration of fluoride in the water, before and after fluoride recharge, and the lactic acid pH change, respectively, were determined. The CAC+SI group demonstrated the highest fluoride release after being recharged with fluoride gel. The CAC+SI group also demonstrated increased lactic acid pH. These findings suggest that a resin-based sealant containing synthesized mesoporous silica and calcium aluminate cement may enhance remineralization due to fluoride release and higher pH.
本研究评估了树脂基窝沟封闭剂中不同类型填料对氟释放、再充注及乳酸中和的影响。树脂基封闭剂中加入了5%（重量/重量）的以下填料：铝酸钙水泥（CAC）、合成介孔二氧化硅（SI）、CAC与SI的混合物（CAC+SI）、玻璃离子粉（GIC）以及经乙酸处理的GIC（GICA）。不含填料的封闭剂作为对照。将样品浸入去离子水或乳酸溶液中，分别测定氟再充注前后水中氟的浓度以及乳酸pH值的变化。在用氟凝胶再充注后，CAC+SI组显示出最高的氟释放量。CAC+SI组的乳酸pH值也有所升高。这些研究结果表明，含有合成介孔二氧化硅和铝酸钙水泥的树脂基封闭剂可能由于氟释放和更高的pH值而增强再矿化作用。
