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子宫内暴露于多环芳烃对肺组织DNA甲基化全基因组模式影响的数据。

Data on the effect of in utero exposure to polycyclic aromatic hydrocarbons on genome-wide patterns of DNA methylation in lung tissues.

作者信息

Fish Trevor J, Benninghoff Abby D

机构信息

Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT 84322, USA.

School of Veterinary Medicine, Utah State University, Logan, UT 84322, USA.

出版信息

Data Brief. 2017 Jun 21;13:498-513. doi: 10.1016/j.dib.2017.06.023. eCollection 2017 Aug.

DOI:10.1016/j.dib.2017.06.023
PMID:28702489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5491394/
Abstract

Data in this article depict patterns of methylation in lung tissues obtained from the offspring of B6129SF1/J dams and 129S1/SvImJ sires exposed to benzo[]pyrene (BaP) or dibenzo[]chrysene (DBC) as compared to non-exposed offspring. Genome-wide methylation of lung tumors in adult offspring was determined using methylated DNA immunoprecipitation (MeDIP) with the NimbleGen mouse DNA methylation CpG island array. This data article refers to the research article "DNA methylation in lung tissues of mouse offspring exposed to polycyclic aromatic hydrocarbons," [1] in which comprehensive data interpretation and analysis are provided.

摘要

本文中的数据描绘了与未接触苯并[a]芘（BaP）或二苯并[a,h]屈（DBC）的后代相比，B6129SF1/J母鼠和129S1/SvImJ公鼠的后代的肺组织中的甲基化模式。使用甲基化DNA免疫沉淀（MeDIP）和NimbleGen小鼠DNA甲基化CpG岛阵列来确定成年后代肺肿瘤的全基因组甲基化。本数据文章参考了研究文章《暴露于多环芳烃的小鼠后代肺组织中的DNA甲基化》[1]，其中提供了全面的数据解释和分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/191e4c8996a5/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/2056810de69f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/72e490fe379f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/7ad9c8685c90/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/89fec396c6eb/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/cd3be102b0ba/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/9358df1f92a7/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/07899093cc44/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/85375ed9c068/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/4c1904d8c9ad/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/ba008c650724/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/191e4c8996a5/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/2056810de69f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/72e490fe379f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/7ad9c8685c90/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/89fec396c6eb/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/cd3be102b0ba/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/9358df1f92a7/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/07899093cc44/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/85375ed9c068/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/4c1904d8c9ad/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/ba008c650724/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de6b/5491394/191e4c8996a5/gr11.jpg

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本文引用的文献

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