Zhou Yujuan, Jie Kecheng, Huang Feihe
State Key Laboratory of Chemical Engineering, Center for Chemistry of High-Performance & Novel Materials, Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China.
Chem Commun (Camb). 2017 Jul 20;53(59):8364-8367. doi: 10.1039/c7cc04779g.
The first selenium-containing pillar[5]arene-based macrocyclic amphiphile was synthesized. This amphiphile self-assembled in water to form vesicles with redox responsiveness. Furthermore, these pillar[5]arene-based vesicles were used in the controlled release of small molecules with DOX as the model compound.
首个含硒的基于柱[5]芳烃的大环两亲分子被合成出来。这种两亲分子在水中自组装形成具有氧化还原响应性的囊泡。此外,这些基于柱[5]芳烃的囊泡被用于以阿霉素作为模型化合物的小分子的控释。