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男男性行为者中艾滋病毒阳性者的无保护肛交:生物医学背景很重要。

Condomless Anal Sex Among HIV-Positive Men Who Have Sex with Men: Biomedical Context Matters.

作者信息

Hughes Alison J, Chen Yea-Hung, Scheer Susan

机构信息

San Francisco Department of Public Health, 25 Van Ness Ave., Suite 500, San Francisco, CA, 94102, USA.

出版信息

AIDS Behav. 2017 Oct;21(10):2886-2894. doi: 10.1007/s10461-017-1852-0.

DOI:10.1007/s10461-017-1852-0
PMID:28702853
Abstract

Data from Medical Monitoring Project was used to determine if partner type is associated with condomless anal sex (CAS) and insertive condomless anal sex (ICAS) among HIV-positive men who have sex with men. Participants reported HIV status and PrEP use of up to five anal sex partners. Partner type was categorized as HIV-positive, HIV status unknown, HIV-negative on PrEP or HIV-negative not on PrEP. To account for correlation of multiple observations per participant, generalized estimating equations were used to calculate adjusted prevalence ratios and 95% confidence intervals of CAS and ICAS. Condom use during anal sex and insertive anal sex varied based on partner type. There was a higher prevalence of CAS and ICAS in partnerships with HIV-positive partners or HIV-negative partners on PrEP compared to HIV-negative partners not on PrEP.

摘要

医学监测项目的数据被用于确定在男男性行为的HIV阳性者中,性伴侣类型是否与无保护肛交(CAS)及插入式无保护肛交(ICAS)相关。参与者报告了其HIV状况以及多达五个肛交性伴侣的暴露前预防(PrEP)使用情况。性伴侣类型被分类为HIV阳性、HIV状况未知、PrEP下的HIV阴性或未使用PrEP的HIV阴性。为了考虑每位参与者多次观察结果之间的相关性,采用广义估计方程来计算CAS和ICAS的调整患病率比及95%置信区间。肛交和插入式肛交时的避孕套使用情况因性伴侣类型而异。与未使用PrEP的HIV阴性伴侣相比,与HIV阳性伴侣或使用PrEP的HIV阴性伴侣发生性行为时,CAS和ICAS的患病率更高

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