Yang Ren-Yin, Sun Jing, Sun Qiu, Yan Chao-Guo
College of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, 225002, China.
Org Biomol Chem. 2017 Aug 2;15(30):6353-6357. doi: 10.1039/c7ob01292f.
Under the combined catalysis of Cu(OTf)/HOTf, the domino annulation reaction of o-arylalkynyl acetophenones with 3-phenacylideneoxindoles in refluxing acetonitrile selectively afforded functionalized spiro[indoline-3,7'-tetrapheno[7,6-bc]furans] and spiro[indeno[1,2-b]naphtho[2,1-d]furan-7,3'-indolines] depending on the electronic effect of the substituents on both substrates.
在Cu(OTf)/HOTf的联合催化下，邻芳基乙炔基苯乙酮与3-苯亚甲基氧化吲哚在回流乙腈中的多米诺环化反应，根据两种底物上取代基的电子效应，选择性地生成了官能化的螺[吲哚啉-3,7'-四苯并[7,6-bc]呋喃]和螺[茚并[1,2-b]萘并[2,1-d]呋喃-7,3'-吲哚啉]。
