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[睡眠呼吸暂停综合征与腹主动脉瘤:动脉瘤患者中睡眠呼吸暂停综合征患病率的研究及相关性研究。对52例患者的临床研究]

[Sleep apnea syndrome and abdominal aortic aneurysm: Study of the prevalence of sleep apnea syndrome in patients with aneurysm and research of association. Clinical study on 52 patients].

作者信息

Hernigou J, Dakhil B, Belmont L, Couffinhal J C, Bagan P

机构信息

Service de chirurgie vasculaire et thoracique, hôpital Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prudhon, 95107 Argenteuil, France.

Service de chirurgie vasculaire et thoracique, hôpital Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prudhon, 95107 Argenteuil, France.

出版信息

J Med Vasc. 2017 May;42(3):162-169. doi: 10.1016/j.jdmv.2017.03.003. Epub 2017 Apr 18.

Abstract

OBJECTIVES

Prevalence of abdominal aortic aneurysms (AAA) in Europe is between 4.1 % and 8.9 %. The risk of rupture of AAA is related to the evolution of its diameter. The role of sleep apnea (SA) remains still discussed. The objective of this study was to study the prevalence of SA in patients presenting with AAA in comparison with the general population as well as the relation between the AAA diameter and the severity of SA.

MATERIALS AND METHODS

Between June 2012 and December 2014, we included all patients referred for surgical treatment of an AAA. All the patients had a preoperative polysomnography and angio-scanner. An apnea/hypopnea index (AHI)>10/h was chosen for the diagnosis of SA. SA prevalence was compared with the prevalence in general population. The patients were also divided into two groups according to the severity of SA: group 1 (no SA and light SAS); group 2 (moderate and severe SA).

RESULTS

Fifty-two patients were included. Fifty-six percent of the patients presented SA - prevalence was significantly higher than in the general population (56 vs. 8 %, P<0.001). The distribution of the two groups was: group 1, n=27 patients, group 2, n=25 patients. AAA diameter and BMI were higher in group 2 than in group 1, respectively 61mm vs. 55mm, P=0.03 and 28 vs. 23, P=0.02.

CONCLUSION

Prevalence of SA in patients with an AAA seems to be significantly higher than in general population. The growth of the aneurysm seems to be linked to the severity of SA.

摘要

目的

欧洲腹主动脉瘤(AAA)的患病率在4.1%至8.9%之间。AAA破裂风险与其直径的变化有关。睡眠呼吸暂停(SA)的作用仍在讨论中。本研究的目的是研究AAA患者中SA的患病率,并与普通人群进行比较,以及AAA直径与SA严重程度之间的关系。

材料与方法

2012年6月至2014年12月期间,我们纳入了所有因AAA接受手术治疗的患者。所有患者均进行了术前多导睡眠图检查和血管扫描仪检查。选择呼吸暂停/低通气指数(AHI)>每小时10次用于SA的诊断。将SA患病率与普通人群的患病率进行比较。患者还根据SA的严重程度分为两组:第1组(无SA和轻度SAS);第2组(中度和重度SA)。

结果

纳入52例患者。56%的患者存在SA,其患病率显著高于普通人群(56%对8%,P<0.001)。两组的分布情况为:第1组,n = 27例患者;第2组,n = 25例患者。第2组的AAA直径和体重指数高于第1组,分别为61毫米对55毫米,P = 0.03;28对23,P = 0.02。

结论

AAA患者中SA的患病率似乎显著高于普通人群。动脉瘤的生长似乎与SA的严重程度有关。

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