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中国山羊埃立克体感染的首次报告。

First report of Ehrlichia infection in goats, China.

作者信息

Zhang Hui, Chang Zhenyu, Mehmood Khalid, Wang Yajing, Rehman Mujeeb Ur, Nabi Fazul, Sabir Ahamad Jawad, Liu Xueting, Wu Xiaoxing, Tian Xinxin, Zhou Donghai

机构信息

College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, People's Republic of China.

College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, People's Republic of China; University College of Veterinary & Animal Sciences, Islamia University of Bahawalpur, 63100, Pakistan.

出版信息

Microb Pathog. 2017 Sep;110:275-278. doi: 10.1016/j.micpath.2017.07.012. Epub 2017 Jul 11.

Abstract

Ehrlichiosis is an emerging infectious disease of domestic animals which is transmitted by ticks. This disease has been reported earlier in most parts of China in dogs, cattle and humans, but there is no published data regarding this disease in goats. The present study provided the evidence of Ehrlichia infection in goats in Wuhan, China on the basis of clinical signs, gross lesions, serum-biochemical, histopathological and PCR. Twenty four goats were presented to the veterinary hospital of Huazhong Agricultural University during July, 2016. The goats were diagnosed for Ehrlichia in monocytic and granulocytic forms by blood smear examination. Further confirmation was done by PCR examination, while histopathological examination revealed degeneration and inflammation in different tissues. The biochemical criterion and blood samples analysis showed significant (P < 0.05) changes. The present study reported that goats are naturally exposed to Ehrlichia infection. To the best of our knowledge, this is the first clinical report of Ehrlichia infection in goats infested with infected ticks.

摘要

埃立克体病是一种由蜱传播的家畜新发传染病。中国大部分地区此前已报道过犬、牛和人类感染这种疾病,但尚无关于山羊感染该疾病的公开数据。本研究基于临床症状、大体病变、血清生化、组织病理学和聚合酶链反应(PCR),提供了中国武汉山羊感染埃立克体的证据。2016年7月,24只山羊被送至华中农业大学兽医院。通过血液涂片检查,诊断这些山羊感染了单核细胞型和粒细胞型埃立克体。通过PCR检查进一步确诊,而组织病理学检查显示不同组织出现变性和炎症。生化指标和血液样本分析显示有显著(P < 0.05)变化。本研究报告称山羊自然暴露于埃立克体感染。据我们所知,这是首例关于感染蜱的山羊感染埃立克体的临床报告。

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