Yang M M, Kwok J S
Am J Chin Med. 1986;14(1-2):46-50. doi: 10.1142/S0192415X86000089.
Experimental studies on the effects of acupuncture, combined Chinese herbs, and opioid peptides on morphine withdrawal symptoms were carried out in 119 addicted rats. Electroacupuncture was found to be the most effective method as it reduced the morphine withdrawal scores to -85%. The combined herbs, Qiang Huo, Gou Teng, Chuan Xion, Fu Zi and Yan Hu Suo suppressed the withdrawal scores of -68%. The opioid peptides, endorphin, enkephalin, and dynorphin, produced marked sedative effect and alleviated the withdrawal symptoms, reducing the scores from -28% to -74%. It is suggested that acupuncture and herbs, being non-opiate and having less side effect, might be used as alternative or supplementary treatment on morphine addiction.
对119只成瘾大鼠进行了针刺、中药复方和阿片肽对吗啡戒断症状影响的实验研究。发现电针是最有效的方法，它能将吗啡戒断评分降低至-85%。中药复方羌活、钩藤、川芎、附子和延胡索使戒断评分降低了-68%。阿片肽、内啡肽、脑啡肽和强啡肽产生了显著的镇静作用，减轻了戒断症状，评分从-28%降至-74%。建议针刺和中药作为非阿片类药物且副作用较小，可作为吗啡成瘾的替代或辅助治疗方法。
