Martinez-Cuezva Alberto, Pastor Aurelia, Cioncoloni Giacomo, Orenes Raul-Angel, Alajarin Mateo, Symes Mark D, Berna Jose
Departamento de Química Orgánica , Facultad de Química , Regional Campus of International Excellence "Campus Mare Nostrum" , Universidad de Murcia , E-30100 , Murcia , Spain . Email:
WestCHEM , School of Chemistry , University of Glasgow , University Avenue , Glasgow G12 8QQ , UK.
Chem Sci. 2015 May 1;6(5):3087-3094. doi: 10.1039/c5sc00790a. Epub 2015 Mar 18.
A cyclic network of chemical reactions has been conceived for exchanging the dynamic behaviour of di(acylamino)pyridine-based rotaxanes and surrogates. X-ray diffraction studies revealed the intercomponent interactions in these interlocked compounds and were consistent with those found in solution by dynamic NMR experiments. This particular binding site was incorporated into a molecular shuttle enabled for accessing two states with an outstanding positional discrimination through chemical manipulation. Furthermore, the ability of the di(acylamino)pyridine domain to associate with external binders with a complementary array of HB donor and acceptor sites was exploited for the advance of an unprecedented electrochemical switch operating through a reversible anion radical recognition process.
人们设想了一个化学反应循环网络，用于交换基于二（酰氨基）吡啶的轮烷及其替代物的动态行为。X射线衍射研究揭示了这些互锁化合物中的组分间相互作用，并且与通过动态核磁共振实验在溶液中发现的相互作用一致。这个特定的结合位点被整合到一个分子穿梭体中，通过化学操作能够以出色的位置区分进入两种状态。此外，利用二（酰氨基）吡啶结构域与具有互补氢键供体和受体位点阵列的外部结合剂缔合的能力，推动了一种前所未有的通过可逆阴离子自由基识别过程运行的电化学开关的发展。
