Unit of Clinical Epidemiology, Cancer Prevention and Research Institute-ISPO, Florence, Italy -
Palliative Care, Pain Therapy, and Rehabiltation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Minerva Anestesiol. 2017 Dec;83(12):1317-1323. doi: 10.23736/S0375-9393.17.12091-2. Epub 2017 Jul 12.
Palliative sedation (PS), the medical act of decreasing a patient's awareness to relieve otherwise intractable suffering, is considered by some commentators to be controversial because of its consequences on residual survival and/or quality of life, and to be inappropriate for treating pure existential suffering. We will argue that PS must be always proportional, i.e. controlling refractory symptoms while keeping the loss of personal values (communication, affective relationships, care relationship) as low as possible, and that imminence of death is necessary too, from an ethical point of view, if a deep and continuous sedation (DCS) is proposed. Moreover, in case of pure existential suffering DCS should only be considered after repeated trials of respite sedation. The use of progressive consent and advance care planning to share the decision with the patient and to involve the family in the decision process as much as the patient desires is another ethical aspect to be pursued. Producing, implementing and sustaining guidelines at the higher scientific and professional level promise to help in improving both clinical and ethical aspects of the practice of PS.
姑息镇静治疗(Palliative sedation,PS),即通过降低患者意识水平来缓解无法控制的痛苦的医疗行为,被一些评论员认为存在争议,因为它会对残留生存和/或生活质量产生影响,并且不适合治疗纯粹的存在性痛苦。我们认为,PS 必须始终保持比例,即控制难治性症状,同时将个人价值的丧失(沟通、情感关系、护理关系)降到最低,如果提出深度持续镇静(Deep and continuous sedation,DCS),从伦理角度来看,还必须考虑到临近死亡。此外,如果是纯粹的存在性痛苦,只有在反复尝试缓解镇静后,才应考虑使用 DCS。使用逐步同意和预先护理计划来与患者共享决策,并尽可能让患者和家属参与决策过程,这是需要遵循的另一个伦理方面。在更高的科学和专业水平上制定、实施和维持指南,有望有助于改善 PS 实践的临床和伦理方面。