Lauterio T J, Decuypere E, Scanes C G
Comp Biochem Physiol A Comp Physiol. 1986;83(4):627-32. doi: 10.1016/0300-9629(86)90701-2.
Body weight, tissue weight and plasma hormone concentrations were determined at 1, 3, 6, 12 and 21 weeks of age in two dwarf strains and one control strain of broiler chickens. Protein synthesis, accretion and degradation rates were determined in the control strain with age. Within each strain, plasma growth hormone (GH) concentrations were greater at 1 and 3 weeks of age and consequently decreased with age. Plasma GH concentrations were greater in the sex-linked dwarf chicken during pubescence and maturity (12 and 21 weeks) compared to the autosomal dwarf and control chickens. Circulating concentrations of 3,5,3' triiodothyronine (T3) were depressed by 70% in sex-linked dwarf birds compared to controls, while thyroxine concentrations did not differ at most time points. These findings support the suggestion that sex-linked dwarf chickens have reduced peripheral conversion of T4 to T3.
在两个矮小型品系和一个对照品系的肉鸡1、3、6、12和21周龄时测定体重、组织重量和血浆激素浓度。在对照品系中测定了不同年龄阶段的蛋白质合成、蓄积和降解率。在每个品系中,血浆生长激素(GH)浓度在1周龄和3周龄时较高,随后随年龄增长而降低。与常染色体矮小鸡和对照鸡相比,性连锁矮小鸡在青春期和成熟期(12周和21周)的血浆GH浓度更高。与对照相比,性连锁矮小鸡体内3,5,3' - 三碘甲状腺原氨酸(T3)的循环浓度降低了70%,而甲状腺素浓度在大多数时间点没有差异。这些发现支持了性连锁矮小鸡外周T4向T3转化减少的观点。