胎牛血清白蛋白和成人牛血清白蛋白对人淋巴细胞体外增殖的影响。

Effect of fetal and adult bovine albumins on human lymphocyte proliferation in vitro.

作者信息

Gallango M L, Maiuri-Ranauro P, Soyano A

出版信息

Comp Biochem Physiol A Comp Physiol. 1986;83(4):771-3. doi: 10.1016/0300-9629(86)90726-7.

Abstract

Fetal and adult bovine albumins were isolated and compared with the commercially obtained fraction V of Cohn, in terms of their ability to support cell proliferation, when added as a supplement to serum-free lymphocyte cultures activated with phytohemagglutinin. It was found that fetal albumin is the least efficient of the three proteins in permitting lymphoproliferation. A difference between the kinetics of proliferation of lymphocyte cultures supplemented with albumin and with serum was also observed.

摘要

分离出胎儿和成年牛白蛋白，并将它们与市售的科恩第五组分进行比较，比较内容为当它们作为补充剂添加到用植物血凝素激活的无血清淋巴细胞培养物中时，支持细胞增殖的能力。结果发现，在促进淋巴细胞增殖方面，胎儿白蛋白是这三种蛋白质中效率最低的。还观察到添加白蛋白的淋巴细胞培养物和添加血清的淋巴细胞培养物在增殖动力学上存在差异。