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切缘分析——游离组织移植是否改善了口腔鳞状细胞癌的肿瘤学预后?

Margin Analysis-Has Free Tissue Transfer Improved Oncologic Outcomes for Oral Squamous Cell Carcinoma?

作者信息

Edwards Sean P

机构信息

Oral and Maxillofacial Surgery Residency Program, University of Michigan, 1500 E Medical Center Drive RM C213, Ann Arbor, MI 48109, USA; Pediatric Maxillofacial Surgery, C.S. Mott Children's Hospital, Michigan Medicine, 1540 E Hospital Drive SPC 4219, Ann Arbor, MI 48109-4219, USA.

出版信息

Oral Maxillofac Surg Clin North Am. 2017 Aug;29(3):377-381. doi: 10.1016/j.coms.2017.05.001.

DOI:10.1016/j.coms.2017.05.001
PMID:28709536
Abstract

Microvascular reconstruction of ablative defects has become a mainstay of contemporary management of head and neck cancer patients. These techniques offer myriad tissue options that vary in character, volume, and components and have vastly improved the esthetic and functional outcomes achieved in this patient population. Although consensus exists regarding the reliability and functional and esthetic benefits of free tissue transfer, the same cannot be said for oncologic outcomes. The increase in resources required for the routine use of free tissue transfer has led to asking this question-Do vascularized free flaps allow for increased surgical margins and improvements in oncologic outcomes?

摘要

对头颈部癌患者进行消融性缺损的微血管重建已成为当代治疗的主要手段。这些技术提供了无数种组织选择,这些组织在特性、体积和成分上各不相同,极大地改善了该患者群体的美学和功能效果。尽管对于游离组织移植的可靠性以及功能和美学益处已达成共识,但肿瘤学结果却并非如此。常规使用游离组织移植所需资源的增加引发了这样一个问题——带血管游离皮瓣能否增加手术切缘并改善肿瘤学结果?

相似文献

1
Margin Analysis-Has Free Tissue Transfer Improved Oncologic Outcomes for Oral Squamous Cell Carcinoma?切缘分析——游离组织移植是否改善了口腔鳞状细胞癌的肿瘤学预后?
Oral Maxillofac Surg Clin North Am. 2017 Aug;29(3):377-381. doi: 10.1016/j.coms.2017.05.001.
2
Primary radical ablative surgery and fibula free-flap reconstruction for T4 oral cavity squamous cell carcinoma with mandibular invasion: oncologic and functional results and their predictive factors.T4期伴下颌骨侵犯的口腔鳞状细胞癌的原发性根治性手术及游离腓骨瓣重建:肿瘤学和功能结果及其预测因素
Eur Arch Otorhinolaryngol. 2017 Jan;274(1):441-449. doi: 10.1007/s00405-016-4219-7. Epub 2016 Jul 20.
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Preoperative Computed Tomography Angiography for Evaluation of Feasibility of Free Flaps in Difficult Reconstruction of Head and Neck.术前计算机断层扫描血管造影术用于评估游离皮瓣在头颈部复杂重建中的可行性
Ann Plast Surg. 2016 Mar;76 Suppl 1:S19-24. doi: 10.1097/SAP.0000000000000690.
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Survival after free flap reconstruction in patients with advanced oral squamous cell carcinoma.晚期口腔鳞状细胞癌患者游离皮瓣重建术后的生存率。
J Oral Maxillofac Surg. 2012 Feb;70(2):453-9. doi: 10.1016/j.joms.2011.02.020.
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Free flap reconstruction in patients with advanced oral squamous cell carcinoma: analysis of patient survival and cancer recurrence.游离皮瓣重建术在晚期口腔鳞状细胞癌患者中的应用:患者生存和癌症复发分析。
Microsurgery. 2012 Nov;32(8):598-604. doi: 10.1002/micr.22009. Epub 2012 Aug 18.
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Microvascular reconstruction of the mouth, jaws, and face: experience of an Australian oral and maxillofacial surgery unit.口腔、颌面部微血管重建:澳大利亚口腔颌面外科单位的经验
J Oral Maxillofac Surg. 2012 May;70(5):e371-7. doi: 10.1016/j.joms.2012.01.016.
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Do predetermined surgical margins compromise oncological safety in computer-assisted head and neck reconstruction?计算机辅助头颈部重建中预定的手术切缘是否会影响肿瘤安全性?
Oral Oncol. 2020 Dec;111:104914. doi: 10.1016/j.oraloncology.2020.104914. Epub 2020 Jul 23.
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Chimaeric subscapular system free flap for complex oro-facial defects.肩胛下系统游离皮瓣修复复杂的口腔颌面缺损。
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The microvascular coupler device for end-to-side venous anastomosis in free tissue transfer for head and neck reconstruction.用于头颈部重建的游离组织移植中静脉端侧吻合的微血管耦合器装置。
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Marking of tumor resection borders for improved radiation planning facilitates reduction of radiation dose to free flap reconstruction in head and neck cancer surgery.标记肿瘤切除边界以改进放射治疗计划,有助于在头颈癌手术中减少对游离皮瓣重建的辐射剂量。
J Craniomaxillofac Surg. 2015 May;43(4):567-73. doi: 10.1016/j.jcms.2015.02.021. Epub 2015 Mar 10.

引用本文的文献

1
Adequacy of surgical margins in oral cancer patients with respect to various types of reconstruction.口腔癌患者不同类型重建手术切缘的充分性
South Asian J Cancer. 2020 Jan-Mar;9(1):34-37. doi: 10.4103/sajc.sajc_366_18.
2
Pectoralis major myocutaneous flap in salvage reconstruction following free flap failure in head and neck cancer surgery.胸大肌肌皮瓣在头颈癌手术中游离皮瓣失败后的挽救性重建中的应用。
J Int Med Res. 2019 Jan;47(1):76-83. doi: 10.1177/0300060518795530. Epub 2018 Dec 5.