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高危面部基底细胞癌Mohs显微外科手术的成本分析

Cost Analysis of Mohs Micrographic Surgery in High-Risk Facial Basal Cell Carcinoma.

作者信息

Blázquez-Sánchez N, de Troya-Martín M, Frieyro-Elicegui M, Fúnez-Liébana R, Martín-Márquez L, Rivas-Ruiz F

机构信息

Servicio de Dermatología, Empresa Pública Hospital Costa del Sol, Marbella, Málaga, España; CIBER Epidemiología y Salud Pública (CIBERESP), Empresa Pública Hospital Costa del Sol, Marbella, Málaga, España.

Servicio de Dermatología, Empresa Pública Hospital Costa del Sol, Marbella, Málaga, España; CIBER Epidemiología y Salud Pública (CIBERESP), Empresa Pública Hospital Costa del Sol, Marbella, Málaga, España.

出版信息

Actas Dermosifiliogr. 2010 Sep;101(7):622-628. doi: 10.1016/j.ad.2010.02.010. Epub 2010 Aug 9.

Abstract

INTRODUCTION

Mohs micrographic surgery (MMS) is the treatment of choice for high-risk facial basal cell carcinoma (BCC) as it offers the greatest chance of cure with maximum preservation of healthy tissue. Its use in Spanish public health care hospitals is still limited, however, due to the controversy surrounding its cost.

OBJECTIVES

To determine the cost of MMS with fresh tissue to treat high-risk facial BCC and compare this to the estimated cost of conventional surgery in a Spanish public hospital. A secondary objective was to identify cost-optimization strategies for MMS.

MATERIAL AND METHODS

Cross-sectional study of a consecutive series of patients with high-risk facial BCC who underwent MMS at the Department of Dermatology at Hospital Costa del Sol in Malaga, Spain between July 2006 and December 2007. We performed a descriptive analysis of the clinical characteristics of the patients and surgical factors. We calculated the total and mean cost of MMS and compared the results to the estimated costs of conventional surgery using patients as their own controls. Differences were analyzed according to tumor site and size, histologic subtype, and recurrence.

RESULTS

Seventy-nine patients (mean age, 62 years) with 81 high-risk facial BCCs, 97.5% of which were primary tumors, underwent MMS. The most common tumor site was the nose (57%) followed by the orbital region (25%). Histology showed that 64% of the tumors were infiltrative or micronodular carcinomas. Tumor-free margins were achieved in all patients, with no more than 2 stages required in 88% of the cases. The most common surgical reconstruction techniques were direct closure (21%) and closure with a local skin flap or graft (71%); the corresponding estimates for conventional surgery were 2% and 89%, respectively. The total and mean cost of MMS was e106,129.07 and e1325.80, respectively (compared to e97 700 and e1208.70 for conventional surgery). The difference in mean costs between MMS and conventional surgery was not significant (P=0.534).

CONCLUSIONS

MMS is a viable, effective technique that does not generate significantly higher costs than conventional surgery in selected patients with high-risk facial BCC. Certain technical and organizational strategies could contribute to optimizing the cost of MMS.

摘要

引言

莫氏显微外科手术(MMS)是治疗高危面部基底细胞癌(BCC)的首选方法,因为它在最大程度保留健康组织的同时,提供了最大的治愈机会。然而,由于其成本方面存在争议,该手术在西班牙公共卫生保健医院中的应用仍然有限。

目的

确定采用新鲜组织的MMS治疗高危面部BCC的成本,并将其与西班牙一家公立医院常规手术的估计成本进行比较。第二个目的是确定MMS的成本优化策略。

材料与方法

对2006年7月至2007年12月期间在西班牙马拉加太阳海岸医院皮肤科接受MMS治疗的一系列连续高危面部BCC患者进行横断面研究。我们对患者的临床特征和手术因素进行了描述性分析。我们计算了MMS的总成本和平均成本,并将结果与以患者自身作为对照的常规手术估计成本进行比较。根据肿瘤部位和大小、组织学亚型以及复发情况分析差异。

结果

79例(平均年龄62岁)患有81处高危面部BCC的患者接受了MMS治疗,其中97.5%为原发性肿瘤。最常见的肿瘤部位是鼻子(57%),其次是眼眶区域(25%)。组织学显示,64%的肿瘤为浸润性或微结节性癌。所有患者均实现了无瘤切缘,88%的病例所需分期不超过2期。最常见的手术重建技术是直接缝合(21%)和局部皮瓣或植皮缝合(71%);常规手术的相应估计分别为2%和89%。MMS的总成本和平均成本分别为106,129.07欧元和1325.80欧元(常规手术分别为97,700欧元和1208.70欧元)。MMS与常规手术的平均成本差异不显著(P=0.534)。

结论

对于部分高危面部BCC患者,MMS是一种可行且有效的技术,其成本并不显著高于常规手术。某些技术和组织策略有助于优化MMS的成本。

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