Martínez-Mata G, Inda-Cunningham D, Medina-López J A, Pacheco-Santiesteban R, Monreal-Romero H
Faculty of Medicine, University of Chihuahua, Chihuahua, Mexico.
School of Dentistry, University of Chihuahua, Chihuahua, Mexico.
J Stomatol Oral Maxillofac Surg. 2017 Dec;118(6):376-378. doi: 10.1016/j.jormas.2017.07.001. Epub 2017 Jul 12.
Lingual congenital cysts are uncommon lesions that alter the functions of speech, swallowing and breathing when they have considerable dimension. They usually appear from birth and increase in size gradually in childhood and adolescence. While there are a considerable number of case reports, the nomenclature and origin of this lesion are controversial. Congenital lingual cysts are composed of an epithelial lining that can show heterogeneous histological features, such as globed, ciliated, squamous and parietal cells, while the wall presents mature connective tissue and eventually smooth muscle. In the present manuscript, we report a case of a congenital lingual cyst in a 13-year-old boy, as well as the immunoexpression of MUC family proteins (MUC-1 and MUC-5AC), hoping to provide data that will help to clarify the possible etiology of this lesion.
舌先天性囊肿是一种罕见的病变，当囊肿尺寸较大时会影响言语、吞咽和呼吸功能。它们通常在出生时就出现，并在儿童期和青春期逐渐增大。虽然有大量的病例报告，但这种病变的命名和起源仍存在争议。先天性舌囊肿由上皮衬里组成，可表现出异质性组织学特征，如球状细胞、纤毛细胞、鳞状细胞和壁细胞，而囊壁则呈现成熟的结缔组织，最终还有平滑肌。在本论文中，我们报告了一例13岁男孩的先天性舌囊肿病例，以及MUC家族蛋白（MUC-1和MUC-5AC）的免疫表达情况，希望能提供有助于阐明该病变可能病因的数据。
