自然杀伤细胞通过抑制或清除树突状细胞来抑制Lyt-2⁺ 细胞毒性T细胞的产生。
NK cells suppress the generation of Lyt-2+ cytolytic T cells by suppressing or eliminating dendritic cells.
作者信息
Gilbertson S M, Shah P D, Rowley D A
出版信息
J Immunol. 1986 May 15;136(10):3567-71.
PMID:2871105
Abstract
Cells highly enriched for natural killer activity suppress the generation of Lyt-2+ cytolytic T cells in one-way mixed lymphocyte cultures. Suppression occurs because natural killer cells suppress or eliminate dendritic cells, which are required for proliferation of both Ly-1+ and Lyt-2+ lymphocytes.
摘要
高度富集天然杀伤活性的细胞在单向混合淋巴细胞培养中抑制Lyt-2+细胞溶解性T细胞的产生。抑制的发生是因为天然杀伤细胞抑制或消除了树突状细胞，而树突状细胞是Ly-1+和Lyt-2+淋巴细胞增殖所必需的。
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