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单侧输尿管肾盂连接部梗阻患儿的影像学检查:是否到了减少检查的时候?

Imaging in children with unilateral ureteropelvic junction obstruction: time to reduce investigations?

机构信息

University Children's Hospital Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland.

University Children's Hospital Tuebingen, Tuebingen, Germany.

出版信息

Eur J Pediatr. 2017 Sep;176(9):1173-1179. doi: 10.1007/s00431-017-2966-0. Epub 2017 Jul 15.

Abstract

UNLABELLED

The objective of the study was the development of an abridged risk-stratified imaging algorithm for the management of children with unilateral ureteropelvic junction obstruction (UPJO). Data on timing, frequency and duration of diagnostic imaging in children with unilateral UPJO was extracted retrospectively. Based on these findings, an abridged imaging algorithm was developed without changing the intended management by the clinicians and the outcome of the individual patient. The potential reduction of imaging studies was analysed and stratified by risk and management groups. The reduction in imaging studies, seen for ultrasound (US) and functional imaging (FI), was 45% each. On average, this is equivalent to 3 US and 1 FI studies less for every patient within the study period. The change was more pronounced in the low-risk groups. Progression of UPJO never occurred after 2 years of age and all secondary surgeries were carried out until the age of 3.

CONCLUSIONS

Although our findings need to be validated by further prospective research, the developed imaging algorithm represents a risk-stratified approach towards less imaging studies in children with unilateral UPJO, and a follow-up beyond 3 years of age should be considered only in selected cases at the discretion of the clinician. What is Known: • ultrasound and functional imaging represent an integral part of therapeutic decision-making in children with unilateral ureteropelvic junction obstruction • imaging studies cannot accurately assess which patients are in need of surgical intervention, therefore close, serial imaging is preferred What is New: • a new, risk-stratified imaging algorithm was developed for the first 3 years of life • applying this algorithm could lead to a considerable reduction of imaging studies, and also the associated risks and health-care costs.

摘要

目的

研究旨在制定简化的风险分层影像学算法,用于单侧肾盂输尿管连接部梗阻(UPJO)患儿的管理。方法:回顾性提取单侧 UPJO 患儿的诊断影像学检查的时间、频率和持续时间数据。基于这些发现,开发了一种简化的影像学算法,而不会改变临床医生的预期管理和患者的个体结果。分析了并按风险和管理组分层了影像学研究的潜在减少量。结果:超声(US)和功能影像学(FI)的影像学研究减少了 45%。平均而言,这相当于在研究期间,每位患者减少 3 次 US 和 1 次 FI 检查。在低风险组中变化更为明显。UPJO 进展从未发生在 2 岁以后,所有二次手术均在 3 岁之前进行。结论:尽管我们的发现需要进一步前瞻性研究来验证,但所开发的影像学算法代表了一种针对单侧 UPJO 患儿减少影像学研究的风险分层方法,并且只有在临床医生的判断下,才应考虑在选定病例中进行 3 岁以上的随访。已知:•超声和功能影像学是单侧肾盂输尿管连接部梗阻患儿治疗决策的重要组成部分。•影像学检查无法准确评估哪些患者需要手术干预,因此优选密切、连续的影像学检查。新内容:•为前 3 年生命制定了新的风险分层影像学算法。•应用该算法可显著减少影像学检查次数,以及相关的风险和医疗保健成本。

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