Delva Iryna I, Delva Mykhaylo Y, Poltorapavlov Volodymyr A
Higher State Educational Establishment of Ukraine, "Ukrainian Medical Stomatological Academy", Poltava, Ukraine.
Wiad Lek. 2017;70(3 pt 2):581-585.
Post-stroke fatigue (PSF) is a common stroke complication with long-term negative consequences.
Assess the rates of certain PSF domains within first 3 months after different acute cerebrovascular events (ACE) and identify clinical factors associated with each PSF domain.
There were examined 285 patients (195 with ischemic strokes, 39 with hemorrhagic strokes and 51 with transient ischemic attacks (TIA)) consequently at hospital stay, in 1 month and in 3 months after ACE. Global PSF and certain PSF domains were measured by multidimensional fatigue inventory-20 scale.
In 1 month and in 3 months after stroke, in comparison with TIA, it has been identified the significant prevalence of only such PSF aspects that are just related to physical activity (physical PSF and activity-related PSF). In multivariate logistic regression analysis the majority of clinical variables as for ischemic strokes (subtype, affected cerebral arterial region, affected cerebral hemisphere, recurrent stroke, post-stroke urinary tract infection, pyrexia, stroke severity according to NIHSS score) and for hemorrhagic strokes (affected cerebral hemisphere, stroke severity according to NIHSS score) were not significantly associated with any PSF domain at any time point after each ACE. On the other hand, in stroke patients it had been found reliable associations between risk of global PSF, activity-related PSF during hospital stay and presence of post-stroke pneumonia, between risk of global PSF, mental PSF in 1 months after stroke and MRS score, between risk of physical PSF in 3 months after stroke and MRS score.
Active prevention of post-stroke pneumonia and early post-stroke rehabilitation probably may be helpful for PSF prevention within first 3 months after stroke.
中风后疲劳（PSF）是一种常见的中风并发症，会产生长期负面影响。
评估不同急性脑血管事件（ACE）后前3个月内某些PSF领域的发生率，并确定与每个PSF领域相关的临床因素。
对285例患者（195例缺血性中风、39例出血性中风和51例短暂性脑缺血发作（TIA））在ACE后住院期间、1个月和3个月时进行了检查。通过多维疲劳量表-20测量整体PSF和某些PSF领域。
在中风后1个月和3个月时，与TIA相比，仅发现与身体活动相关的PSF方面（身体PSF和活动相关PSF）有显著的患病率。在多因素逻辑回归分析中，大多数缺血性中风（亚型、受影响的脑动脉区域、受影响的脑半球、复发性中风、中风后尿路感染、发热、根据NIHSS评分的中风严重程度）和出血性中风（受影响的脑半球、根据NIHSS评分的中风严重程度）的临床变量在每次ACE后的任何时间点均与任何PSF领域无显著相关性。另一方面，在中风患者中发现，整体PSF风险、住院期间活动相关PSF与中风后肺炎的存在之间，整体PSF风险、中风后1个月时的精神PSF与MRS评分之间，中风后3个月时的身体PSF风险与MRS评分之间存在可靠关联。
积极预防中风后肺炎和早期中风后康复可能有助于在中风后前3个月内预防PSF。
