Neduba A A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(3):424-8.
Clinical regularities in the formation of resistance to therapy in schizophrenic patients make it possible to identify 4 groups of therapy resistance: (1) resistance due to clinical factors (regularities of the process); (2) resistance due to both clinical and therapeutical factors (predicted insufficient cure); (3) resistance due to therapeutic factors in connection with adaptation to drugs and therapeutic errors (inadequate or insufficiently intensive treatment); (4) idiopathic resistance. This systematics of states resistant to therapy may contribute to differentiation of their treatment.
精神分裂症患者治疗抵抗形成的临床规律使得识别4种治疗抵抗类型成为可能：(1) 由临床因素（病程规律）导致的抵抗；(2) 由临床和治疗因素共同导致的抵抗（预计治愈不足）；(3) 与药物适应及治疗失误相关的治疗因素导致的抵抗（治疗不充分或强度不足）；(4) 特发性抵抗。这种对治疗抵抗状态的分类有助于其治疗的差异化。
