充血性心力衰竭中的自主神经系统。

The autonomic nervous system in congestive heart failure.

作者信息

Francis G S, Cohn J N

出版信息

Annu Rev Med. 1986;37:235-47. doi: 10.1146/annurev.me.37.020186.001315.

DOI:10.1146/annurev.me.37.020186.001315

Abstract

Congestive heart failure is a complex clinical syndrome characterized by striking abnormalities of the autonomic nervous system. The mechanisms and biological importance of these disturbances are not clearly defined. Nonetheless, it is possible that autonomic disturbances play an important role in the pathophysiology and prognosis of heart failure, and therefore drugs that alter autonomic function may provide additional therapeutic options in the management of this syndrome.

摘要

充血性心力衰竭是一种复杂的临床综合征，其特征为自主神经系统存在显著异常。这些紊乱的机制及生物学重要性尚未明确界定。尽管如此，自主神经紊乱在心力衰竭的病理生理学及预后中可能发挥重要作用，因此，改变自主神经功能的药物或许可为该综合征的治疗提供更多选择。