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用燕麦粉和普通豆粉制作的曲奇饼干改善了糖尿病大鼠的血清标志物。

Cookies elaborated with oat and common bean flours improved serum markers in diabetic rats.

作者信息

Pérez-Ramírez Iza F, Becerril-Ocampo Laura J, Reynoso-Camacho Rosalía, Herrera Mayra D, Guzmán-Maldonado S Horacio, Cruz-Bravo Raquel K

机构信息

Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, México.

Instituto Nacional de Investigaciones Forestales, Agrícolas y Pecuarias (INIFAP), Campus Zacatecas, Campo Experimental Zacatecas, Calera, México.

出版信息

J Sci Food Agric. 2018 Feb;98(3):998-1007. doi: 10.1002/jsfa.8548. Epub 2017 Aug 24.

Abstract

BACKGROUND

Common beans have been associated with anti-diabetic effects, due to its high content of bioactive compounds. Nevertheless, its consumption has decreased worldwide. Therefore, there is an increasing interest in the development of novel functional foods elaborated with common beans. The aim of this study was to evaluate the anti-diabetic effect of oat-bean flour cookies, and to analyze its bioactive composition, using commercial oat-wheat cookies for comparative purposes.

RESULTS

Oat-bean cookies (1.2 g kg ) slightly decreased serum glucose levels (∼1.1-fold) and increased insulin levels (∼1.2-fold) in diabetic rats, reducing the hyperglycemic peak in healthy rats (∼1.1-fold). Oat-bean cookies (0.8 and 1.2 g kg ) exerted a greater hypolipidemic effect than commercial oat-wheat cookies (1.2 g kg ), as observed in decreased serum triglycerides and low-density lipoprotein cholesterol. Furthermore, the supplementation with 1.2 g kg oat-bean cookies decreased atherogenic index and serum C-reactive protein levels, suggesting their cardioprotective potential. The beneficial effect of oat-bean cookies was associated with their high content of dietary fiber and galacto oligosaccharides, as well as chlorogenic acid, rutin, protocatechuic acid, β-sitosterol and soyasaponins.

CONCLUSION

These results suggest that common beans can be used as functional ingredients for the elaboration of cookies with anti-diabetic effects. © 2017 Society of Chemical Industry.

摘要

背景

由于普通豆富含生物活性化合物,其与抗糖尿病作用相关。然而,全球范围内其消费量有所下降。因此,人们对开发以普通豆为原料的新型功能性食品的兴趣日益浓厚。本研究旨在评估燕麦 - 豆粉饼干的抗糖尿病作用,并分析其生物活性成分,同时使用市售燕麦 - 小麦饼干作对比。

结果

燕麦 - 豆饼干(1.2 g/kg)可使糖尿病大鼠的血清葡萄糖水平略有下降(约1.1倍),胰岛素水平升高(约1.2倍),并降低健康大鼠的高血糖峰值(约1.1倍)。如血清甘油三酯和低密度脂蛋白胆固醇降低所示,燕麦 - 豆饼干(0.8和1.2 g/kg)比市售燕麦 - 小麦饼干(1.2 g/kg)具有更强的降血脂作用。此外,补充1.2 g/kg的燕麦 - 豆饼干可降低动脉粥样硬化指数和血清C反应蛋白水平,表明其具有心脏保护潜力。燕麦 - 豆饼干的有益作用与其膳食纤维、低聚半乳糖以及绿原酸、芦丁、原儿茶酸、β-谷甾醇和大豆皂苷的高含量有关。

结论

这些结果表明普通豆可作为功能性成分用于制作具有抗糖尿病作用的饼干。©2017化学工业协会。

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