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一例继发于双侧膈神经麻痹的进行性端坐呼吸和肩部疼痛病例。

A case of progressive orthopnoea and shoulder pain secondary to bilateral diaphragmatic paralysis.

作者信息

Herbert Anna, Khan Waseem Asrar, Madi Salem

机构信息

Respiratory Medicine, Royal Albert Edward Infirmary, Wigan, UK.

出版信息

BMJ Case Rep. 2017 Jul 18;2017:bcr-2017-219892. doi: 10.1136/bcr-2017-219892.

Abstract

A 45-year-old man with a raised body mass index presented with an acute history of right lower chest pain and increasing breathlessness. C reactive protein, D dimer and cardiac echocardiography were negative, with mild bibasal atelectasis the only positive reported finding from erect chest X-ray and CT pulmonary angiogram. He was discharged with antibiotics for a chest infection. He remained severely breathless and was referred to the sleep-related breathing disorders clinic. He described shoulder pain, daytime tiredness and sleeping upright due to a ââ'¬Ëœsuffocatingââ'¬â"¢ sensation. The video demonstrates the clinical findings. The CT topogram confirmed bilateral diaphragmatic paralysis. Spirometry demonstrated an 80% reduction in forced vital capacity in the supine position, when compared with erect. Consultation with a neurologist yielded the diagnosis of neuralgic amyotrophy, leading to bilateral diaphragmatic paralysis. The respiratory symptoms have been controlled with night-time non-invasive ventilation, allowing him to sleep supine.

摘要

一名体重指数升高的45岁男性,出现右下胸痛和呼吸急促加重的急性病史。C反应蛋白、D二聚体和心脏超声心动图检查均为阴性,直立胸部X线和CT肺血管造影仅报告有轻度双肺底肺不张这一阳性发现。他因胸部感染接受抗生素治疗后出院。他仍严重呼吸急促,被转诊至睡眠相关呼吸障碍诊所。他描述有肩部疼痛、日间疲倦,因“窒息”感而需直立睡眠。视频展示了临床检查结果。CT平扫证实双侧膈神经麻痹。肺功能测定显示,与直立位相比,仰卧位时用力肺活量降低了80%。咨询神经科医生后诊断为神经性肌萎缩,导致双侧膈神经麻痹。夜间无创通气已控制了呼吸症状,使他能够仰卧睡眠。

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本文引用的文献

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Severe Acute Orthopnea: Ipilimumab-Induced Bilateral Phrenic Nerve Neuropathy.
Lung. 2015 Aug;193(4):611-3. doi: 10.1007/s00408-015-9716-8. Epub 2015 May 9.
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Neuralgic amyotrophy presenting with bilateral vocal cord paralysis in a child: a case report.
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Neuralgic amyotrophy: A rare cause of bilateral diaphragmatic paralysis.
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