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Hospital-Acquired Infections(Archived)

作者信息

Monegro Alberto F., Muppidi Vijayadershan, Regunath Hariharan

机构信息

University of Missouri

Indiana University health

Abstract

Hospital-acquired infections, or healthcare-associated infections (HAI), are nosocomially acquired infections that are typically absent or might be incubating at admission. These infections are usually acquired after hospitalization and manifest 48 hours after admission to the hospital. The infections are monitored closely by agencies such as the National Healthcare Safety Network (NHSN) of the Center for Disease Control and Prevention (CDC). This surveillance is done to prevent HAI and improve patient safety. HAI infections include central line-associated bloodstream infections (CLABSI), catheter-associated urinary tract infections (CAUTI), surgical site infections (SSI), Hospital-acquired Pneumonia (HAP), Ventilator-associated Pneumonia (VAP), and  infections. For the last few decades, hospitals have taken hospital-acquired infections seriously. Several hospitals have established infection tracking and surveillance systems and robust prevention strategies to reduce the rate of hospital-acquired infections. The impact of hospital-acquired infections is seen not just at an individual patient level but also at the community level, as they have been linked to multidrug-resistant infections. Identifying patients with risk factors for hospital-acquired infections and multidrug-resistant infections is very important in preventing and minimizing these infections.  Based on the guidelines from both the Infectious Disease Society of America (IDSA) and the American Thoracic Society (ATS), the definitions of Pneumonia have been changed to better identify patients at risk for multidrug-resistant (MDR) pathogens. This, in turn, is aimed at avoiding the overuse of antibiotics. Healthcare-acquired Pneumonia, or HCAP, which was widely used previously, has been made obsolete. The term Hospital-acquired Pneumonia or HAP has replaced HCAP. Per the IDSA guidelines, Hospital-acquired Pneumonia is defined as "pneumonia that occurs 48 hours or more after admission to the hospital and did not appear to be incubating at the time of admission". According to IDSA, Ventilator-associated pneumonia or VAP is defined as "pneumonia that develops more than 48 to 72 hours after endotracheal intubation".Both HAP and VAP are associated with poorer outcomes and significant morbidity and mortality worldwide.

摘要

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