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蛛网膜下腔出血

Subarachnoid Hemorrhage

作者信息

Ziu Endrit, Khan Suheb Mahammed Z., Mesfin Fassil B.

机构信息

University of Wisconsin

University of Texas, Long School of Medicine

PMID:28722987
Abstract

Overall, about 20% of strokes are hemorrhagic, with SAH and Intracerebral hemorrhage (ICH) each accounting for 10%. Subarachnoid space is described as a space between the arachnoid membrane and the pia mater. It consists of the cerebrospinal fluid and the blood vessels that supply different areas of the brain. A subarachnoid hemorrhage (SAH) is defined as the accumulation of blood in the space between the arachnoid membrane and the pia mater around the brain referred to as the subarachnoid space.  The etiology of SAH can be either nontraumatic (about 85% are secondary to aneurysm rupture) or traumatic in nature. In this review, we shall discuss the various aspects of nontraumatic SAH. Most nontraumatic causes of SAH (~ 85%) are caused by the rupture of an intracranial aneurysm. The remaining 15-20% of patients presenting with SAH do not have a vascular lesion on the initial digital subtraction angiography. Regardless of the cause, a SAH is often a devastating clinical event with substantial mortality and high morbidity among survivors. Prehospital care is critical and involves triaging the patient with attention to the airway, breathing, and circulation to a hospital with neurocritical/neurosurgical expertise. The classic presentation is often a sudden-onset, severe headache typically described as the "worst headache of my life". Treatments are based on randomized controlled studies and prospective cohort studies. A SAH has a prolonged course of illness and is complicated by various factors not limited to seizures, vasospasm, hydrocephalus, and delayed cerebral ischemia (DCI).

摘要

总体而言,约20%的中风为出血性,蛛网膜下腔出血(SAH)和脑出血(ICH)各占10%。蛛网膜下腔被描述为蛛网膜和软脑膜之间的间隙。它由脑脊液和供应大脑不同区域的血管组成。蛛网膜下腔出血(SAH)被定义为血液在大脑周围蛛网膜和软脑膜之间的间隙(即蛛网膜下腔)积聚。SAH的病因可以是非创伤性的(约85%继发于动脉瘤破裂)或创伤性的。在本综述中,我们将讨论非创伤性SAH的各个方面。SAH的大多数非创伤性病因(约85%)是由颅内动脉瘤破裂引起的。其余15 - 20%表现为SAH的患者在初次数字减影血管造影时没有血管病变。无论病因如何,SAH通常是一种毁灭性的临床事件,死亡率高,幸存者的发病率也高。院前护理至关重要,包括将患者分诊到具有神经重症/神经外科专业知识的医院,并注意气道、呼吸和循环。典型表现通常是突然发作的严重头痛,通常被描述为“我一生中最严重的头痛”。治疗基于随机对照研究和前瞻性队列研究。SAH病程较长,并伴有各种并发症,不限于癫痫发作、血管痉挛、脑积水和迟发性脑缺血(DCI)。

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