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伴有少量腹膜转移癌的不可切除胃癌患者的计算机断层扫描特征

Computed tomographic characteristics for patients with unresectable gastric cancer harboring low-volume peritoneal carcinomatosis.

作者信息

Guo Jhe-Cyuan, Chang Chin-Chen, Yang Chung-Yi, Liao Bin-Chi, Liau Jau-Yu, Chang Chin-Hao, Yeh Kun-Huei

机构信息

Department of Oncology, National Taiwan University Hospital, Taipei City, Taiwan.

Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei City, Taiwan.

出版信息

Med Oncol. 2017 Aug;34(8):143. doi: 10.1007/s12032-017-1004-4. Epub 2017 Jul 19.

Abstract

Although current staging workups could differentiate most patients with operable from inoperable advanced gastric cancers, there are still some patients with low-volume peritoneal carcinomatosis, defined as only metastasis with multiple subcentimeter lesions in peritoneum, receiving unnecessary open-close procedures. The computed tomography (CT) of the patients with unresectable advanced gastric cancer harboring low-volume peritoneal carcinomatosis was retrospectively identified and then thoroughly reviewed by two independent radiologists unaware of the peritoneal carcinomatosis status. Of the 798 patients with newly diagnosed gastric cancer between January 2007 and December 2010, 52 patients harboring advanced gastric cancer with low-volume peritoneal carcinomatosis receiving surgery with curative intent were identified. Descriptive statistic was used for the radiologic characteristics. The most common radiologic characteristic of CT was omental fat stranding (57.7%), followed by omental clustered subcentimeter nodules (53.8%), distant enlarged lymph node (40.4%), distant grouping of small lymph nodes (36.5%), peritoneal nodules or thickening (34.6%), minimal loculated ascites (21.2%), intestinal wall thickening or irregularity (9.6%), and hydronephrosis or hydroureter without stone or urothelial lesion (5.8%). Comprehensively reviewing the radiologic characteristics of CT may identify the patients harboring advanced gastric cancer with low-volume peritoneal carcinomatosis.

摘要

尽管目前的分期检查可以区分大多数可手术和不可手术的晚期胃癌患者,但仍有一些低容量腹膜转移癌患者,即仅表现为腹膜多发小于1厘米病变的转移,接受了不必要的开腹-关腹手术。对患有不可切除的晚期胃癌且伴有低容量腹膜转移癌的患者的计算机断层扫描(CT)进行回顾性识别,然后由两名不了解腹膜转移癌状况的独立放射科医生进行全面审查。在2007年1月至2010年12月期间新诊断的798例胃癌患者中,识别出52例患有晚期胃癌且伴有低容量腹膜转移癌并接受了根治性手术的患者。对影像学特征进行描述性统计。CT最常见的影像学特征是网膜脂肪浸润(57.7%),其次是网膜簇状小于1厘米结节(53.8%)、远处肿大淋巴结(40.4%)、远处小淋巴结聚集(36.5%)、腹膜结节或增厚(34.6%)、少量局限性腹水(21.2%)、肠壁增厚或不规则(9.6%)以及无结石或尿路上皮病变的肾盂积水或输尿管积水(5.8%)。综合审查CT的影像学特征可能识别出患有晚期胃癌且伴有低容量腹膜转移癌的患者。

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